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MGI:Bax
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bax | |
| Protein Name(s) | BCL2-associated X protein, | |
| External Links | ||
| MGI | MGI:99702 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001101 |
response to acid |
MGI:MGI:77140 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001541 |
ovarian follicle development |
MGI:MGI:1860555 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2176699 |
P |
From MGI |
||
| GO:0001541 |
ovarian follicle development |
MGI:MGI:3697561 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001764 |
neuron migration |
MGI:MGI:3531599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001776 |
leukocyte homeostasis |
MGI:MGI:1929371 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0001776 |
leukocyte homeostasis |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0001777 |
T cell homeostatic proliferation |
MGI:MGI:76784 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001777 |
T cell homeostatic proliferation |
MGI:MGI:894988 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001782 |
B cell homeostasis |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0001782 |
B cell homeostasis |
MGI:MGI:3588597 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001783 |
B cell apoptotic process |
MGI:MGI:3588597 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0001783 |
B cell apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001822 |
kidney development |
MGI:MGI:894988 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:1203837 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:3028818 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:3042308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98834 |
P |
From MGI |
||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:3688960 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:108093 |
P |
From MGI |
||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001836 |
release of cytochrome c from mitochondria |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001844 |
protein insertion into mitochondrial membrane involved in induction of apoptosis |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0001974 |
blood vessel remodeling |
MGI:MGI:3692135 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0002262 |
myeloid cell homeostasis |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0002352 |
B cell negative selection |
MGI:MGI:3588597 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0002358 |
B cell homeostatic proliferation |
MGI:MGI:76784 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0002904 |
positive regulation of B cell apoptotic process |
MGI:MGI:2152245 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97250 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3700463 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:1928555 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:85084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:1202651 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1344851 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1345899 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1861517 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1931634 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3511755 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3615714 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2137769 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2179627 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2667259 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3042308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:108093 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:3511755 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3615714 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3836857 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005741 |
mitochondrial outer membrane |
MGI:MGI:2673116 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005741 |
mitochondrial outer membrane |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005741 |
mitochondrial outer membrane |
MGI:MGI:3607027 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005757 |
mitochondrial permeability transition pore complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:2667259 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2137769 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2178871 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2179627 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2667259 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3583493 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3607027 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3836857 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006309 |
DNA fragmentation involved in apoptotic nuclear change |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006687 |
glycosphingolipid metabolic process |
MGI:MGI:3797995 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0006808 |
regulation of nitrogen utilization |
MGI:MGI:894988 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:1203837 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:1332944 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:1351384 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:3042308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98834 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:67275 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:1344924 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:67275 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:2667259 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:3041326 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:3575207 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:3692043 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158306 |
P |
From MGI |
||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:5009404 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006922 |
cleavage of lamin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006927 |
transformed cell apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1196094 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0007007 |
inner mitochondrial membrane organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007008 |
outer mitochondrial membrane organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007281 |
germ cell development |
MGI:MGI:1860555 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2176699 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:1860555 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2176699 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:2177346 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:76784 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:2663581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387665 |
P |
From MGI |
||
| GO:0007548 |
sex differentiation |
MGI:MGI:3054131 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008053 |
mitochondrial fusion |
MGI:MGI:3662939 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2159364 |
P |
From MGI |
||
| GO:0008053 |
mitochondrial fusion |
MGI:MGI:3665364 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2159364 |
P |
From MGI |
||
| GO:0008053 |
mitochondrial fusion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008283 |
cell proliferation |
MGI:MGI:1860799 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0008283 |
cell proliferation |
MGI:MGI:892190 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:1860799 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008289 |
lipid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008584 |
male gonad development |
MGI:MGI:3610512 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:894988 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0008624 |
induction of apoptosis by extracellular signals |
MGI:MGI:2676517 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008624 |
induction of apoptosis by extracellular signals |
MGI:MGI:2677915 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008624 |
induction of apoptosis by extracellular signals |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008629 |
induction of apoptosis by intracellular signals |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008629 |
induction of apoptosis by intracellular signals |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008634 |
negative regulation of survival gene product expression |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008635 |
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c |
MGI:MGI:1203837 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008635 |
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c |
MGI:MGI:2178486 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0008635 |
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008637 |
apoptotic mitochondrial changes |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008637 |
apoptotic mitochondrial changes |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009566 |
fertilization |
MGI:MGI:1860555 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2176699 |
P |
From MGI |
||
| GO:0009611 |
response to wounding |
MGI:MGI:2676517 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0009636 |
response to toxin |
MGI:MGI:1196094 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009636 |
response to toxin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009651 |
response to salt stress |
MGI:MGI:3654719 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:102845 |
P |
From MGI |
||
| GO:0009791 |
post-embryonic development |
MGI:MGI:894988 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0010212 |
response to ionizing radiation |
MGI:MGI:1352316 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107202 |
P |
From MGI |
||
| GO:0010212 |
response to ionizing radiation |
MGI:MGI:3512739 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0010248 |
establishment or maintenance of transmembrane electrochemical gradient |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010332 |
response to gamma radiation |
MGI:MGI:3722566 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0010524 |
positive regulation of calcium ion transport into cytosol |
MGI:MGI:3527292 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0015267 |
channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:67275 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0019987 |
negative regulation of anti-apoptosis |
MGI:MGI:82784 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88139 |
P |
From MGI |
||
| GO:0021854 |
hypothalamus development |
MGI:MGI:3054131 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0021987 |
cerebral cortex development |
MGI:MGI:3054131 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0030264 |
nuclear fragmentation involved in apoptotic nuclear change |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030264 |
nuclear fragmentation involved in apoptotic nuclear change |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031072 |
heat shock protein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031558 |
induction of apoptosis in response to chemical stimulus |
MGI:MGI:3692043 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158306 |
P |
From MGI |
||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:2137769 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:2178871 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:3028818 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032091 |
negative regulation of protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032461 |
positive regulation of protein oligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032471 |
reduction of endoplasmic reticulum calcium ion concentration |
MGI:MGI:3527292 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0032976 |
release of matrix enzymes from mitochondria |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0033137 |
negative regulation of peptidyl-serine phosphorylation |
MGI:MGI:3527292 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0033599 |
regulation of mammary gland epithelial cell proliferation |
MGI:MGI:1337911 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0034644 |
cellular response to UV |
MGI:MGI:3042308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98834 |
P |
From MGI |
||
| GO:0035108 |
limb morphogenesis |
MGI:MGI:1929371 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0035234 |
germ cell programmed cell death |
MGI:MGI:2680318 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96677 |
P |
From MGI |
||
| GO:0035234 |
germ cell programmed cell death |
MGI:MGI:2680318 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0035234 |
germ cell programmed cell death |
MGI:MGI:3691300 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96974 |
P |
From MGI |
||
| GO:0042475 |
odontogenesis of dentin-containing tooth |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:1347718 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:79740 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:79740 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002475 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:1329774 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:1928435 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:1933803 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:2177346 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3512739 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3579917 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3581932 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3654719 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:102845 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3691300 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96974 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3692135 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:3722566 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:86208 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98834 |
P |
From MGI |
||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:894988 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:2676517 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043496 |
regulation of protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043497 |
regulation of protein heterodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043523 |
regulation of neuron apoptotic process |
MGI:MGI:3821405 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:79659 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1196093 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1277631 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1352316 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107202 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1355025 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95824 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1860799 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1861056 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95813 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:1929535 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158306 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3531599 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3580738 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3586962 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3590457 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3691384 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3692043 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158306 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3694443 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:3695831 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:82821 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:86927 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88139 |
P |
From MGI |
||
| GO:0043653 |
mitochondrial fragmentation involved in apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044445 |
cytosolic part |
MGI:MGI:1202651 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045136 |
development of secondary sexual characteristics |
MGI:MGI:3580738 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0045333 |
cellular respiration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046666 |
retinal cell programmed cell death |
MGI:MGI:2677551 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0046674 |
induction of retinal programmed cell death |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046902 |
regulation of mitochondrial membrane permeability |
MGI:MGI:3042308 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:108093 |
P |
From MGI |
||
| GO:0046930 |
pore complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:1095590 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:1931634 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:2385423 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:82784 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0048087 |
positive regulation of developmental pigmentation |
MGI:MGI:894988 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:99702 |
P |
From MGI |
||
| GO:0048147 |
negative regulation of fibroblast proliferation |
MGI:MGI:2675761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0048515 |
spermatid differentiation |
MGI:MGI:3610512 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0048597 |
post-embryonic camera-type eye morphogenesis |
MGI:MGI:3692135 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0048678 |
response to axon injury |
MGI:MGI:3586962 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0048872 |
homeostasis of number of cells |
MGI:MGI:1861517 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0048872 |
homeostasis of number of cells |
MGI:MGI:1929371 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0048873 |
homeostasis of number of cells within a tissue |
MGI:MGI:3054131 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857249 |
P |
From MGI |
||
| GO:0048873 |
homeostasis of number of cells within a tissue |
MGI:MGI:3653046 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0051087 |
chaperone binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051259 |
protein oligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051260 |
protein homooligomerization |
MGI:MGI:2677915 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051260 |
protein homooligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051281 |
positive regulation of release of sequestered calcium ion into cytosol |
MGI:MGI:3694443 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0051400 |
BH domain binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:1860799 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88138 |
P |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:1931634 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:2153579 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97383 |
P |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:3029650 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:3527374 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:3695621 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95819 |
P |
From MGI |
||
| GO:0051434 |
BH3 domain binding |
MGI:MGI:2180577 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0051434 |
BH3 domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051726 |
regulation of cell cycle |
MGI:MGI:3588597 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0051881 |
regulation of mitochondrial membrane potential |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060011 |
Sertoli cell proliferation |
MGI:MGI:2153276 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0060041 |
retina development in camera-type eye |
MGI:MGI:1277631 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0060058 |
positive regulation of apoptotic process involved in mammary gland involution |
MGI:MGI:1337911 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857429 |
P |
From MGI |
||
| GO:0060068 |
vagina development |
MGI:MGI:1929371 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0070059 |
apoptosis in response to endoplasmic reticulum stress |
MGI:MGI:2667259 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0070059 |
apoptosis in response to endoplasmic reticulum stress |
MGI:MGI:3575207 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1097161 |
P |
From MGI |
||
| GO:0070059 |
apoptosis in response to endoplasmic reticulum stress |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071310 |
cellular response to organic substance |
MGI:MGI:2662654 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0097136 |
Bcl-2 family protein complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:1900103 |
positive regulation of endoplasmic reticulum unfolded protein response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2001244 |
positive regulation of intrinsic apoptotic signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
NOT |
GO:0051881 |
regulation of mitochondrial membrane potential |
MGI:MGI:3028818 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gillardon F et al. (1995) Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci Lett 192: 85-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Rucker EB 3rd et al. (2000) Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis. Mol Endocrinol 14: 1038-52 PubMed GONUTS page
- ↑ Greenfeld CR et al. (2007) BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries. Reproduction 133: 107-16 PubMed GONUTS page
- ↑ 4.0 4.1 Sun W et al. (2004) Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene Bax. J Neurosci 24: 11205-13 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Lindsten T et al. (2000) The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell 6: 1389-99 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Hutcheson J et al. (2005) Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis. J Exp Med 201: 1949-60 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Knudson CM et al. (1995) Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270: 96-9 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Knudson CM & Korsmeyer SJ (1997) Bcl-2 and Bax function independently to regulate cell death. Nat Genet 16: 358-63 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Takeuchi O et al. (2005) Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease. Proc Natl Acad Sci U S A 102: 11272-7 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Jürgensmeier JM et al. (1998) Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci U S A 95: 4997-5002 PubMed GONUTS page
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