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MGI:Bag6
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bag6 ( synonyms: Bat3, D17H6S52E, G3, Scythe ) | |
| Protein Name(s) | BCL2-associated athanogene 6, | |
| External Links | ||
| MGI | MGI:1919439 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001822 |
kidney development |
MGI:MGI:3703386 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002474 |
antigen processing and presentation of peptide antigen via MHC class I |
MGI:MGI:4887294 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688344 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3774040 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1339529 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001029140 |
C |
From MGI |
||
| GO:0005829 |
cytosol |
MGI:MGI:3774040 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:4887294 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0007130 |
synaptonemal complex assembly |
MGI:MGI:3808636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:3808636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007420 |
brain development |
MGI:MGI:3703386 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009790 |
embryo development |
MGI:MGI:3703386 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016568 |
chromatin modification |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From MGI |
||
| GO:0018393 |
internal peptidyl-lysine acetylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:3703386 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030544 |
Hsp70 protein binding |
MGI:MGI:3808636 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031593 |
polyubiquitin binding |
MGI:MGI:4887294 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0032435 |
negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:3808636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042771 |
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:3703386 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043022 |
ribosome binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045861 |
negative regulation of proteolysis |
MGI:MGI:3774040 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0050821 |
protein stabilization |
MGI:MGI:3774040 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0050821 |
protein stabilization |
MGI:MGI:3808636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070059 |
apoptosis in response to endoplasmic reticulum stress |
MGI:MGI:3774040 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070628 |
proteasome binding |
MGI:MGI:4887294 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0071816 |
tail-anchored membrane protein insertion into ER membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071818 |
BAT3 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Desmots F et al. (2005) The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol 25: 10329-37 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Minami R et al. (2010) BAG-6 is essential for selective elimination of defective proteasomal substrates. J Cell Biol 190: 637-50 PubMed GONUTS page
- ↑ Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Desmots F et al. (2008) Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis. J Biol Chem 283: 3264-71 PubMed GONUTS page
- ↑ Ozaki T et al. (1999) Cloning and characterization of rat BAT3 cDNA. DNA Cell Biol 18: 503-12 PubMed GONUTS page
- ↑ 6.0 6.1 Reed JC et al. (2003) Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res 13: 1376-88 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Sasaki T et al. (2008) Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis. J Cell Biol 182: 449-58 PubMed GONUTS page
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