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MGI:B2m

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) B2m ( synonyms: beta 2 microglobulin, beta2-m, Ly-m11 )
Protein Name(s) beta-2 microglobulin,
External Links
MGI MGI:88127

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001916

positive regulation of T cell mediated cytotoxicity

MGI:MGI:3611636
PMID:16299293[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0002237

response to molecule of bacterial origin

MGI:MGI:3611636
PMID:16299293[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0002474

antigen processing and presentation of peptide antigen via MHC class I

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0490

P

From MGI

GO:0002481

antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent

MGI:MGI:3611636
PMID:16299293[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0005515

protein binding

MGI:MGI:3037219
PMID:14735325[2]

IPI: Inferred from Physical Interaction

UniProtKB:P14427

F

From MGI

GO:0005515

protein binding

MGI:MGI:3808676
PMID:16920948[3]

IPI: Inferred from Physical Interaction

UniProtkB:Q8HWE7
UniProtKB:Q8HWE6

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07151

C

From MGI

GO:0006968

cellular defense response

MGI:MGI:1926968
PMID:2685607[4]

TAS: Traceable Author Statement

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:50291
PMID:1538753[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0033077

T cell differentiation in thymus

MGI:MGI:3817343
PMID:18776904[6]

IGI: Inferred from Genetic Interaction

MGI:MGI:95663

P

From MGI

GO:0042026

protein refolding

MGI:MGI:3808676
PMID:16920948[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042612

MHC class I protein complex

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0490

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Ugrinovic S et al. (2005) H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar Typhimurium infection recognize proteins released by Salmonella serovar Typhimurium. Infect Immun 73: 8002-8 PubMed GONUTS page
  2. Lilić M et al. (2004) Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain. Immunogenetics 55: 740-7 PubMed GONUTS page
  3. 3.0 3.1 Kajikawa M et al. (2006) MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression. J Immunol 177: 3108-15 PubMed GONUTS page
  4. Zijlstra M et al. (1989) Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature 342: 435-8 PubMed GONUTS page
  5. Attaya M et al. (1992) Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature 355: 647-9 PubMed GONUTS page
  6. Wang L et al. (2008) Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol 9: 1122-30 PubMed GONUTS page
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