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MGI:B2m
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | B2m ( synonyms: beta 2 microglobulin, beta2-m, Ly-m11 ) | |
| Protein Name(s) | beta-2 microglobulin, | |
| External Links | ||
| MGI | MGI:88127 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001916 |
positive regulation of T cell mediated cytotoxicity |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002237 |
response to molecule of bacterial origin |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0002474 |
antigen processing and presentation of peptide antigen via MHC class I |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0490 |
P |
From MGI |
||
| GO:0002481 |
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent |
MGI:MGI:3611636 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3037219 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3808676 |
IPI: Inferred from Physical Interaction |
UniProtkB:Q8HWE7 |
F |
From MGI |
||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005615 |
extracellular space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006968 |
cellular defense response |
MGI:MGI:1926968 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:50291 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0033077 |
T cell differentiation in thymus |
MGI:MGI:3817343 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95663 |
P |
From MGI |
||
| GO:0042026 |
protein refolding |
MGI:MGI:3808676 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042612 |
MHC class I protein complex |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0490 |
C |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Ugrinovic S et al. (2005) H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar Typhimurium infection recognize proteins released by Salmonella serovar Typhimurium. Infect Immun 73: 8002-8 PubMed GONUTS page
- ↑ Lilić M et al. (2004) Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain. Immunogenetics 55: 740-7 PubMed GONUTS page
- ↑ 3.0 3.1 Kajikawa M et al. (2006) MHC class I-like MILL molecules are beta2-microglobulin-associated, GPI-anchored glycoproteins that do not require TAP for cell surface expression. J Immunol 177: 3108-15 PubMed GONUTS page
- ↑ Zijlstra M et al. (1989) Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature 342: 435-8 PubMed GONUTS page
- ↑ Attaya M et al. (1992) Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature 355: 647-9 PubMed GONUTS page
- ↑ Wang L et al. (2008) Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol 9: 1122-30 PubMed GONUTS page