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MGI:Atxn1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Atxn1 ( synonyms: Atx1, Sca1 ) | |
| Protein Name(s) | ataxin 1, | |
| External Links | ||
| MGI | MGI:104783 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003723 |
RNA binding |
MGI:MGI:3522382 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3693029 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008266 |
poly(U) RNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:1270078 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181805 |
P |
From MGI |
||
| GO:0008542 |
visual learning |
MGI:MGI:1270078 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181805 |
P |
From MGI |
||
| GO:0016363 |
nuclear matrix |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0034046 |
poly(G) RNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042326 |
negative regulation of phosphorylation |
MGI:MGI:3774689 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429435 |
P |
From MGI |
||
| GO:0042405 |
nuclear inclusion body |
MGI:MGI:3522382 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042405 |
nuclear inclusion body |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043231 |
intracellular membrane-bounded organelle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043569 |
negative regulation of insulin-like growth factor receptor signaling pathway |
MGI:MGI:3774689 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429435 |
P |
From MGI |
||
| GO:0043621 |
protein self-association |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3774689 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429435 |
P |
From MGI |
||
| GO:0051168 |
nuclear export |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
MGI:MGI:1270078 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2181805 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Irwin S et al. (2005) RNA association and nucleocytoplasmic shuttling by ataxin-1. J Cell Sci 118: 233-42 PubMed GONUTS page
- ↑ Serra HG et al. (2006) RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice. Cell 127: 697-708 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Matilla A et al. (1998) Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation. J Neurosci 18: 5508-16 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Gatchel JR et al. (2008) The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7. Proc Natl Acad Sci U S A 105: 1291-6 PubMed GONUTS page
