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MGI:Atrx
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Atrx ( synonyms: DXHXS6677E, HP1-BP38, Hp1bp2, Rad54, XH2, Xnp ) | |
| Protein Name(s) | alpha thalassemia/mental retardation syndrome X-linked homolog (human), | |
| External Links | ||
| MGI | MGI:103067 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000228 |
nuclear chromosome |
MGI:MGI:2150845 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:2682084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:3051070 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:3760176 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:3057220 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004386 |
helicase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0347 |
F |
From MGI |
||
| GO:0004386 |
helicase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3051070 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3760176 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3760176 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From MGI |
||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0030900 |
forebrain development |
MGI:MGI:3528132 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3528480 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0070087 |
chromo shadow domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sutherland HG et al. (2001) Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Hum Mol Genet 10: 1995-2011 PubMed GONUTS page
- ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
- ↑ 3.0 3.1 Ishov AM et al. (2004) Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX. J Cell Sci 117: 3807-20 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Nan X et al. (2007) Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc Natl Acad Sci U S A 104: 2709-14 PubMed GONUTS page
- ↑ Wang L et al. (2004) Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins. Biochem Biophys Res Commun 325: 302-7 PubMed GONUTS page
- ↑ Bérubé NG et al. (2005) The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest 115: 258-67 PubMed GONUTS page
