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MGI:Atr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Atr | |
| Protein Name(s) | ataxia telangiectasia and Rad3 related, | |
| External Links | ||
| MGI | MGI:108028 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000077 |
DNA damage checkpoint |
MGI:MGI:2679752 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0000077 |
DNA damage checkpoint |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0001741 |
XY body |
MGI:MGI:3774244 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:3053255 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:3522367 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3522367 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:3053255 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:3053255 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:3584078 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008156 |
negative regulation of DNA replication |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0018105 |
peptidyl-serine phosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032405 |
MutLalpha complex binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032407 |
MutSalpha complex binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0034644 |
cellular response to UV |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043393 |
regulation of protein binding |
MGI:MGI:3584078 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046777 |
protein autophosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071480 |
cellular response to gamma radiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090399 |
replicative senescence |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yuan L et al. (2003) DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase. J Biol Chem 278: 42812-20 PubMed GONUTS page
- ↑ Yang F et al. (2008) Meiotic failure in male mice lacking an X-linked factor. Genes Dev 22: 682-91 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Sengupta S et al. (2004) Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. J Cell Biol 166: 801-13 PubMed GONUTS page
- ↑ 4.0 4.1 Polci R et al. (2004) NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res 64: 8800-3 PubMed GONUTS page
- ↑ 5.0 5.1 Ishii H et al. (2005) Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis. Proc Natl Acad Sci U S A 102: 9655-60 PubMed GONUTS page
