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MGI:Atn1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Atn1 ( synonyms: Atr1, atrophin-1, Drpla ) | |
| Protein Name(s) | atrophin 1, | |
| External Links | ||
| MGI | MGI:104725 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3624573 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:3624573 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1100526 |
F |
From MGI |
||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3624573 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2656131 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3624573 |
IC: Inferred by Curator |
GO:0003714 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2656131 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0008432 |
JUN kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009404 |
toxin metabolic process |
MGI:MGI:2656131 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016363 |
nuclear matrix |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016477 |
cell migration |
MGI:MGI:3844415 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019904 |
protein domain specific binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030011 |
maintenance of cell polarity |
MGI:MGI:3844415 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0031252 |
cell leading edge |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045664 |
regulation of neuron differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0050827 |
toxin receptor binding |
MGI:MGI:2656131 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2001141 |
regulation of RNA biosynthetic process |
MGI:MGI:3624573 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1100526 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Zhang CL et al. (2006) Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev 20: 1308-20 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Nucifora FC Jr et al. (2003) Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. J Biol Chem 278: 13047-55 PubMed GONUTS page
- ↑ 3.0 3.1 Hou R & Sibinga NE (2009) Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells. J Biol Chem 284: 6955-65 PubMed GONUTS page
