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MGI:Asph
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Asph ( synonyms: aspartyl beta-hydroxylase, BAH, calsequestrin-binding protein, cI-37, jumbug, junctate, Junctin ) | |
| Protein Name(s) | aspartate-beta-hydroxylase, | |
| External Links | ||
| MGI | MGI:1914186 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004597 |
peptide-aspartate beta-dioxygenase activity |
MGI:MGI:1928177 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0256 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007389 |
pattern specification process |
MGI:MGI:2177999 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179287 |
P |
From MGI |
||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:2177999 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88039 |
P |
From MGI |
||
| GO:0010524 |
positive regulation of calcium ion transport into cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1928177 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0223 |
F |
From MGI |
||
| GO:0018193 |
peptidyl-amino acid modification |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0030176 |
integral to endoplasmic reticulum membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0031585 |
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032541 |
cortical endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033198 |
response to ATP |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035108 |
limb morphogenesis |
MGI:MGI:2177999 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179287 |
P |
From MGI |
||
| GO:0042264 |
peptidyl-aspartic acid hydroxylation |
MGI:MGI:2177999 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0060021 |
palate development |
MGI:MGI:2177999 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179287 |
P |
From MGI |
||
| GO:0060325 |
face morphogenesis |
MGI:MGI:2177999 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2179287 |
P |
From MGI |
||
| GO:0070588 |
calcium ion transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071277 |
cellular response to calcium ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Dinchuk JE et al. (2000) Aspartyl beta -hydroxylase (Asph) and an evolutionarily conserved isoform of Asph missing the catalytic domain share exons with junctin. J Biol Chem 275: 39543-54 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Dinchuk JE et al. (2002) Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia. J Biol Chem 277: 12970-7 PubMed GONUTS page
