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MGI:Ash2l

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ash2l
Protein Name(s) ash2 (absent, small, or homeotic)-like (Drosophila),
External Links
MGI MGI:1344416

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0005515

protein binding

MGI:MGI:3773768
PMID:17825402[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q8BX09

F

From MGI

GO:0005515

protein binding

MGI:MGI:4819465
PMID:20463296[2]

IPI: Inferred from Physical Interaction

UniProtKB:P70323

F

From MGI

GO:0005515

protein binding

MGI:MGI:5285127
PMID:21477851[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q8BX09

F

From MGI

GO:0005515

protein binding

MGI:MGI:5315331
PMID:21335234[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q8BX09

F

From MGI

GO:0005634

nucleus

MGI:MGI:3718866
PMID:17500065[5]

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:3718866
PMID:17500065[5]

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

P

From MGI

GO:0016568

chromatin modification

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From MGI

GO:0035097

histone methyltransferase complex

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

C

From MGI

GO:0035097

histone methyltransferase complex

MGI:MGI:3718866
PMID:17500065[5]

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

C

From MGI

GO:0043627

response to estrogen stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

P

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

F

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4819465
PMID:20463296[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:98493

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048188

Set1C/COMPASS complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

C

From MGI

GO:0051568

histone H3-K4 methylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UBL3

P

From MGI

GO:0071339

MLL1 complex

MGI:MGI:4419079
PMID:15960975[6]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. De Santa F et al. (2007) The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 130: 1083-94 PubMed GONUTS page
  2. 2.0 2.1 Stoller JZ et al. (2010) Ash2l interacts with Tbx1 and is required during early embryogenesis. Exp Biol Med (Maywood) 235: 569-76 PubMed GONUTS page
  3. Ang YS et al. (2011) Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145: 183-97 PubMed GONUTS page
  4. Jiang H et al. (2011) Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144: 513-25 PubMed GONUTS page
  5. 5.0 5.1 5.2 Cho YW et al. (2007) PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J Biol Chem 282: 20395-406 PubMed GONUTS page
  6. Dou Y et al. (2005) Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell 121: 873-85 PubMed GONUTS page
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