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MGI:Arx

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Arx
Protein Name(s) aristaless related homeobox,
External Links
MGI MGI:1097716

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001764

neuron migration

MGI:MGI:2389512
PMID:12379852[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238
UniProtKB-KW:KW-0371

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009057

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005634

nucleus

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007411

axon guidance

MGI:MGI:3574008
PMID:15677725[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007411

axon guidance

MGI:MGI:3709215
PMID:17460091[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2679972

P

From MGI

GO:0021759

globus pallidus development

MGI:MGI:3709215
PMID:17460091[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2679972

P

From MGI

GO:0021772

olfactory bulb development

MGI:MGI:3574008
PMID:15677725[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0021800

cerebral cortex tangential migration

MGI:MGI:3709215
PMID:17460091[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2679972

P

From MGI

GO:0021831

embryonic olfactory bulb interneuron precursor migration

MGI:MGI:3574008
PMID:15677725[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0021846

cell proliferation in forebrain

MGI:MGI:3574008
PMID:15677725[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0021853

cerebral cortex GABAergic interneuron migration

MGI:MGI:3709215
PMID:17460091[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2679972

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030900

forebrain development

MGI:MGI:2389512
PMID:12379852[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0042127

regulation of cell proliferation

MGI:MGI:2389512
PMID:12379852[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0046622

positive regulation of organ growth

MGI:MGI:3574008
PMID:15677725[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2429693

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Kitamura K et al. (2002) Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet 32: 359-69 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Yoshihara S et al. (2005) Arx homeobox gene is essential for development of mouse olfactory system. Development 132: 751-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Colombo E et al. (2007) Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation. J Neurosci 27: 4786-98 PubMed GONUTS page
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