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MGI:Arntl
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Arntl ( synonyms: Arnt3, bHLHe5, Bmal1, MOP3 ) | |
| Protein Name(s) | aryl hydrocarbon receptor nuclear translocator-like, | |
| External Links | ||
| MGI | MGI:1096381 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000060 |
protein import into nucleus, translocation |
MGI:MGI:2669067 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000982 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity |
MGI:MGI:5297789 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
MGI:MGI:2683983 |
IC: Inferred by Curator |
GO:0045944 |
F |
From MGI |
||
| GO:0001190 |
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription |
MGI:MGI:5306311 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:1276614 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:1276614 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2153999 |
ISA: Inferred from Sequence Alignment |
EMBL:AJ318060 |
F |
From MGI |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2179885 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1276614 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3807720 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3807721 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3829113 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4881368 |
IPI: Inferred from Physical Interaction |
UniProtKB:O08785 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:5294528 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2669067 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:3625767 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2179885 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007623 |
circadian rhythm |
MGI:MGI:1928563 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180361 |
P |
From MGI |
||
| GO:0007623 |
circadian rhythm |
MGI:MGI:2179885 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007623 |
circadian rhythm |
MGI:MGI:2183702 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007623 |
circadian rhythm |
MGI:MGI:2667759 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007623 |
circadian rhythm |
MGI:MGI:2669067 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007623 |
circadian rhythm |
MGI:MGI:3703208 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:2153999 |
ISA: Inferred from Sequence Alignment |
EMBL:AJ318060 |
F |
From MGI |
||
| GO:0017162 |
aryl hydrocarbon receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042176 |
regulation of protein catabolic process |
MGI:MGI:2669067 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043425 |
bHLH transcription factor binding |
MGI:MGI:2388855 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0043425 |
bHLH transcription factor binding |
MGI:MGI:5306311 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2683983 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3625767 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:99698 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3838062 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:5297789 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:2388855 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0051879 |
Hsp90 protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Kondratov RV et al. (2003) BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. Genes Dev 17: 1921-32 PubMed GONUTS page
- ↑ 2.0 2.1 Hamaguchi H et al. (2004) Expression of the gene for Dec2, a basic helix-loop-helix transcription factor, is regulated by a molecular clock system. Biochem J 382: 43-50 PubMed GONUTS page
- ↑ 3.0 3.1 Kawamoto T et al. (2004) A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochem Biophys Res Commun 313: 117-24 PubMed GONUTS page
- ↑ 4.0 4.1 Sato F et al. (2004) Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. Eur J Biochem 271: 4409-19 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Takahata S et al. (1998) Transcriptionally active heterodimer formation of an Arnt-like PAS protein, Arnt3, with HIF-1a, HLF, and clock. Biochem Biophys Res Commun 248: 789-94 PubMed GONUTS page
- ↑ 6.0 6.1 Avivi A et al. (2001) Biological clock in total darkness: the Clock/MOP3 circadian system of the blind subterranean mole rat. Proc Natl Acad Sci U S A 98: 13751-6 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Cheng MY et al. (2002) Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 417: 405-10 PubMed GONUTS page
- ↑ Nakahata Y et al. (2008) The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134: 329-40 PubMed GONUTS page
- ↑ Asher G et al. (2008) SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 134: 317-28 PubMed GONUTS page
- ↑ Langmesser S et al. (2008) Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK. BMC Mol Biol 9: 41 PubMed GONUTS page
- ↑ Asher G et al. (2010) Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. Cell 142: 943-53 PubMed GONUTS page
- ↑ Ozber N et al. (2010) Identification of two amino acids in the C-terminal domain of mouse CRY2 essential for PER2 interaction. BMC Mol Biol 11: 69 PubMed GONUTS page
- ↑ 13.0 13.1 Yujnovsky I et al. (2006) Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc Natl Acad Sci U S A 103: 6386-91 PubMed GONUTS page
- ↑ Bunger MK et al. (2000) Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103: 1009-17 PubMed GONUTS page
- ↑ Preitner N et al. (2002) The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 110: 251-60 PubMed GONUTS page
- ↑ Dudley CA et al. (2003) Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice. Science 301: 379-83 PubMed GONUTS page
- ↑ Kojima S et al. (2007) LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1. Proc Natl Acad Sci U S A 104: 1859-64 PubMed GONUTS page
- ↑ 18.0 18.1 Honma S et al. (2002) Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature 419: 841-4 PubMed GONUTS page
- ↑ Duffield GE et al. (2009) A role for Id2 in regulating photic entrainment of the mammalian circadian system. Curr Biol 19: 297-304 PubMed GONUTS page
