Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Arhgap1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Arhgap1 ( synonyms: Cdc42GAP, p50rhoGAP )
Protein Name(s) Rho GTPase activating protein 1,
External Links
MGI MGI:2445003

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001726

ruffle

MGI:MGI:3576987
PMID:15860730[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005096

GTPase activator activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0343

F

From MGI

GO:0005100

Rho GTPase activator activity

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q07960

F

From MGI

GO:0005100

Rho GTPase activator activity

MGI:MGI:2447568
PMID:10699171[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3778569
PMID:18331715[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9ERR1

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008936
InterPro:IPR000198

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3576987
PMID:15860730[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008936
InterPro:IPR000198

P

From MGI

GO:0007264

small GTPase mediated signal transduction

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q07960

P

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0729

F

From MGI

GO:0030675

Rac GTPase activator activity

MGI:MGI:2447568
PMID:10699171[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0031252

cell leading edge

MGI:MGI:3778569
PMID:18331715[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0032321

positive regulation of Rho GTPase activity

MGI:MGI:2447568
PMID:10699171[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032321

positive regulation of Rho GTPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q07960

P

From MGI

GO:0032855

positive regulation of Rac GTPase activity

MGI:MGI:2447568
PMID:10699171[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043087

regulation of GTPase activity

MGI:MGI:2447568
PMID:10699171[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PCG8

C

From MGI

GO:0043547

positive regulation of GTPase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0343

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Pixley FJ et al. (2005) BCL6 suppresses RhoA activity to alter macrophage morphology and motility. J Cell Sci 118: 1873-83 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Prakash SK et al. (2000) Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA. Hum Mol Genet 9: 477-88 PubMed GONUTS page
  3. 3.0 3.1 Shen Y et al. (2008) Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. Dev Cell 14: 342-53 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox