Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Arf6

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Arf6
Protein Name(s) ADP-ribosylation factor 6,
External Links
MGI MGI:99435

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0001726

ruffle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P62332

C

From MGI

GO:0001726

ruffle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

C

From MGI

GO:0001889

liver development

MGI:MGI:3653957
PMID:16880525[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3662650

P

From MGI

GO:0003924

GTPase activity

MGI:MGI:4948831
PMID:16751103[2]

TAS: Traceable Author Statement

F

From MGI

GO:0005525

GTP binding

MGI:MGI:1095420
PMID:8947846[3]

TAS: Traceable Author Statement

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4948831
PMID:16751103[2]

TAS: Traceable Author Statement

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR024156

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1095420
PMID:8947846[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005768

endosome

MGI:MGI:1095420
PMID:8947846[3]

TAS: Traceable Author Statement

C

From MGI

GO:0005768

endosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

C

From MGI

GO:0005768

endosome

MGI:MGI:4948831
PMID:16751103[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005769

early endosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P62332

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0333

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1095420
PMID:8947846[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P62332

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

C

From MGI

GO:0005938

cell cortex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

C

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:3653957
PMID:16880525[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3662650

P

From MGI

GO:0007264

small GTPase mediated signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR024156

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0015031

protein transport

MGI:MGI:1095420
PMID:8947846[3]

TAS: Traceable Author Statement

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016192

vesicle-mediated transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0931

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0030838

positive regulation of actin filament polymerization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

P

From MGI

GO:0030866

cortical actin cytoskeleton organization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

P

From MGI

GO:0031527

filopodium membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

C

From MGI

GO:0031529

ruffle organization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

P

From MGI

GO:0031996

thioesterase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

F

From MGI

GO:0034143

regulation of toll-like receptor 4 signaling pathway

MGI:MGI:4948831
PMID:16751103[2]

NAS: Non-traceable Author Statement

P

From MGI

GO:0034394

protein localization at cell surface

MGI:MGI:4948831
PMID:16751103[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0035020

regulation of Rac protein signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

P

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0051489

regulation of filopodium assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62330

P

From MGI

GO:0055037

recycling endosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P62332

C

From MGI

GO:0060998

regulation of dendritic spine development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P62332

P

From MGI

GO:0060998

regulation of dendritic spine development

MGI:MGI:4887338
PMID:16325184[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0090004

positive regulation of establishment of protein localization in plasma membrane

MGI:MGI:4948831
PMID:16751103[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0090162

establishment of epithelial cell polarity

MGI:MGI:4420836
PMID:20080746[5]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Suzuki T et al. (2006) Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol 26: 6149-56 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Kagan JC & Medzhitov R (2006) Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell 125: 943-55 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Hosaka M et al. (1996) Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6). J Biochem 120: 813-9 PubMed GONUTS page
  4. Miyazaki H et al. (2005) The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation. FEBS Lett 579: 6834-8 PubMed GONUTS page
  5. Ikenouchi J & Umeda M (2010) FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex. Proc Natl Acad Sci U S A 107: 748-53 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox