GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Arap3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Arap3 ( synonyms: Centd3, DRAG1 ) | |
| Protein Name(s) | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3, | |
| External Links | ||
| MGI | MGI:2147274 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001726 |
ruffle |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005096 |
GTPase activator activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
F |
From MGI |
||
| GO:0005100 |
Rho GTPase activator activity |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3511766 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005547 |
phosphatidylinositol-3,4,5-trisphosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008060 |
ARF GTPase activator activity |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008360 |
regulation of cell shape |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0030027 |
lamellipodium |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032312 |
regulation of ARF GTPase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0032321 |
positive regulation of Rho GTPase activity |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035021 |
negative regulation of Rac protein signal transduction |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035024 |
negative regulation of Rho protein signal transduction |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043325 |
phosphatidylinositol-3,4-bisphosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0343 |
P |
From MGI |
||
| GO:0043547 |
positive regulation of GTPase activity |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
|
NOT |
GO:0030675 |
Rac GTPase activator activity |
MGI:MGI:3511766 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 I ST et al. (2004) ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner. J Cell Sci 117: 6071-84 PubMed GONUTS page
