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MGI:Araf

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Araf ( synonyms: A-Raf, Araf1 )
Protein Name(s) v-raf murine sarcoma 3611 viral oncogene homolog,
External Links
MGI MGI:88065

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000165

MAPK cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

P

From MGI

GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000186

activation of MAPKK activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

P

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10398

F

From MGI

GO:0004709

MAP kinase kinase kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

F

From MGI

GO:0005057

receptor signaling protein activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003116

F

From MGI

GO:0005515

protein binding

MGI:MGI:1197353
PMID:9488663[1]

IPI: Inferred from Physical Interaction

UniProtKB:P08556

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002219

C

From MGI

GO:0005626

insoluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2671672
PMID:12931191[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005829

cytosol

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P14056

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003116

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0033138

positive regulation of peptidyl-serine phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10398

P

From MGI

GO:0035556

intracellular signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002219

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P10398

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Vavvas D et al. (1998) Identification of Nore1 as a potential Ras effector. J Biol Chem 273: 5439-42 PubMed GONUTS page
  2. Danial NN et al. (2003) BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424: 952-6 PubMed GONUTS page
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