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MGI:Aqp1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Aqp1 ( synonyms: CHIP28 ) | |
| Protein Name(s) | aquaporin 1, | |
| External Links | ||
| MGI | MGI:103201 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000299 |
integral to membrane of membrane fraction |
MGI:MGI:2386456 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0003094 |
glomerular filtration |
MGI:MGI:3606554 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0003097 |
renal water transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005215 |
transporter activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005223 |
intracellular cGMP activated cation channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005267 |
potassium channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005372 |
water transmembrane transporter activity |
MGI:MGI:1352967 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005372 |
water transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:3805139 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3583388 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:3805139 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2180433 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2387728 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3616340 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3708206 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3718874 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3796400 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005887 |
integral to plasma membrane |
MGI:MGI:1926639 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005903 |
brush border |
MGI:MGI:3608308 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005903 |
brush border |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005903 |
brush border |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006182 |
cGMP biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006813 |
potassium ion transport |
MGI:MGI:4457239 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:1329306 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:1331263 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:1352967 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:1926639 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:1929327 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:2387728 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1351654 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3612624 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3616340 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3616723 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3617943 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3688642 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3693419 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3722591 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3784745 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:3796400 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0006833 |
water transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006833 |
water transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006884 |
cell volume homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009925 |
basal plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0010592 |
positive regulation of lamellipodium assembly |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010634 |
positive regulation of epithelial cell migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015079 |
potassium ion transmembrane transporter activity |
MGI:MGI:4457239 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0015168 |
glycerol transmembrane transporter activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015168 |
glycerol transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015250 |
water channel activity |
MGI:MGI:1926639 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0015250 |
water channel activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015250 |
water channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015670 |
carbon dioxide transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015696 |
ammonium transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015793 |
glycerol transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015793 |
glycerol transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016323 |
basolateral plasma membrane |
MGI:MGI:3608308 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016323 |
basolateral plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016323 |
basolateral plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:3608308 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:3848874 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0019233 |
sensory perception of pain |
MGI:MGI:3616910 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0019725 |
cellular homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0020003 |
symbiont-containing vacuole |
MGI:MGI:4457239 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0022857 |
transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030104 |
water homeostasis |
MGI:MGI:3617038 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0030184 |
nitric oxide transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030185 |
nitric oxide transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030335 |
positive regulation of cell migration |
MGI:MGI:4352615 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0030950 |
establishment or maintenance of actin cytoskeleton polarity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031526 |
brush border membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031965 |
nuclear membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032127 |
dense core granule membrane |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032809 |
neuronal cell body membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032940 |
secretion by cell |
MGI:MGI:3805139 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0033267 |
axon part |
MGI:MGI:3718874 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0033363 |
secretory granule organization |
MGI:MGI:3805139 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0033554 |
cellular response to stress |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034644 |
cellular response to UV |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035377 |
transepithelial water transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035378 |
carbon dioxide transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035379 |
carbon dioxide transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042060 |
wound healing |
MGI:MGI:4352615 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0042383 |
sarcolemma |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042493 |
response to drug |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043679 |
axon terminus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0044241 |
lipid digestion |
MGI:MGI:1932595 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0045177 |
apical part of cell |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045766 |
positive regulation of angiogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046875 |
ephrin receptor binding |
MGI:MGI:1859095 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0046878 |
positive regulation of saliva secretion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048146 |
positive regulation of fibroblast proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048593 |
camera-type eye morphogenesis |
MGI:MGI:2180433 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0051458 |
corticotropin secretion |
MGI:MGI:3805139 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0051739 |
ammonia transmembrane transporter activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0055085 |
transmembrane transport |
MGI:MGI:1352967 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070062 |
extracellular vesicular exosome |
MGI:MGI:4367398 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0070295 |
renal water absorption |
MGI:MGI:1196668 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1353208 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107387 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1353208 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1354610 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1858888 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1929327 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1333777 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:1929327 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:2387728 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:3607623 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1314647 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:3640845 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070295 |
renal water absorption |
MGI:MGI:3700886 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857807 |
P |
From MGI |
||
| GO:0070301 |
cellular response to hydrogen peroxide |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071241 |
cellular response to inorganic substance |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071260 |
cellular response to mechanical stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071280 |
cellular response to copper ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071288 |
cellular response to mercury ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071300 |
cellular response to retinoic acid |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071320 |
cellular response to cAMP |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071456 |
cellular response to hypoxia |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071472 |
cellular response to salt stress |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071474 |
cellular hyperosmotic response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071549 |
cellular response to dexamethasone stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071732 |
cellular response to nitric oxide |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071805 |
potassium ion transmembrane transport |
MGI:MGI:4457239 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071805 |
potassium ion transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0085018 |
maintenance of symbiont-containing vacuole via substance secreted by host |
MGI:MGI:4457239 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0085018 |
maintenance of symbiont-containing vacuole via substance secreted by host |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Mennone A et al. (2002) Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice. Am J Physiol Gastrointest Liver Physiol 283: G739-46 PubMed GONUTS page
- ↑ Hashimoto S et al. (2004) Compensation of proximal tubule malabsorption in AQP1-deficient mice without TGF-mediated reduction of GFR. Acta Physiol Scand 181: 455-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Yang B et al. (2000) Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem 275: 2686-92 PubMed GONUTS page
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- ↑ Verkman AS et al. (2000) Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice. Exp Physiol 85 Spec No: 233S-241S PubMed GONUTS page
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