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MGI:Aph1c
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Aph1c | |
| Protein Name(s) | anterior pharynx defective 1c homolog (C. elegans), | |
| External Links | ||
| MGI | MGI:1915568 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001656 |
metanephros development |
MGI:MGI:2675249 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004175 |
endopeptidase activity |
MGI:MGI:3527313 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2385110 |
F |
From MGI |
||
| GO:0007219 |
Notch signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0914 |
P |
From MGI |
||
| GO:0008233 |
peptidase activity |
MGI:MGI:2445234 |
ISA: Inferred from Sequence Alignment |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2445234 |
ISA: Inferred from Sequence Alignment |
C |
From MGI |
|||
| GO:0016485 |
protein processing |
MGI:MGI:2445234 |
ISA: Inferred from Sequence Alignment |
P |
From MGI |
|||
| GO:0016485 |
protein processing |
MGI:MGI:3527313 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:2385110 |
P |
From MGI |
||
| GO:0043085 |
positive regulation of catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cheng HT et al. (2003) Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney. Development 130: 5031-42 PubMed GONUTS page
- ↑ 2.0 2.1 Ma G et al. (2005) APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development. J Neurosci 25: 192-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Lee SF et al. (2002) Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch. J Biol Chem 277: 45013-9 PubMed GONUTS page
eim |
m cont.np |
p cont. |
