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MGI:Anxa1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Anxa1 ( synonyms: Anx-1, Anx-A1, Lpc-1, Lpc1 )
Protein Name(s) annexin A1,
External Links
MGI MGI:96819

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001533

cornified envelope

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

C

From MGI

GO:0002674

negative regulation of acute inflammatory response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0004859

phospholipase inhibitor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002388

F

From MGI

GO:0005198

structural molecule activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001464
InterPro:IPR018502
InterPro:IPR018252
InterPro:IPR002388

F

From MGI

GO:0005515

protein binding

MGI:MGI:2683818
PMID:14506282[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9ESD7

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

F

From MGI

GO:0005544

calcium-dependent phospholipid binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

F

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0005929

cilium

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0969

C

From MGI

GO:0007049

cell cycle

MGI:MGI:2661244
PMID:12553880[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449710

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2661244
PMID:12553880[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449710

P

From MGI

GO:0007166

cell surface receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0018149

peptide cross-linking

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

P

From MGI

GO:0019834

phospholipase A2 inhibitor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

F

From MGI

GO:0030073

insulin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0030216

keratinocyte differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

P

From MGI

GO:0030674

protein binding, bridging

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

F

From MGI

GO:0031340

positive regulation of vesicle fusion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P04083

P

From MGI

GO:0031394

positive regulation of prostaglandin biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0031966

mitochondrial membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0042127

regulation of cell proliferation

MGI:MGI:2661244
PMID:12553880[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449710

P

From MGI

GO:0042383

sarcolemma

MGI:MGI:2683818
PMID:14506282[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

F

From MGI

GO:0042995

cell projection

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

C

From MGI

GO:0046632

alpha-beta T cell differentiation

MGI:MGI:4943619
PMID:20139728[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0050482

arachidonic acid secretion

MGI:MGI:2661244
PMID:12553880[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2449710

P

From MGI

GO:0050709

negative regulation of protein secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

GO:0070301

cellular response to hydrogen peroxide

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

P

From MGI

contributes_to

GO:0003697

single-stranded DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

F

From MGI

contributes_to

GO:0003727

single-stranded RNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07150

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lennon NJ et al. (2003) Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing. J Biol Chem 278: 50466-73 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Croxtall JD et al. (2003) Attenuation of glucocorticoid functions in an Anx-A1-/- cell line. Biochem J 371: 927-35 PubMed GONUTS page
  3. Paschalidis N et al. (2010) Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Cell Cycle 9: 784-93 PubMed GONUTS page
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