GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Ankrd1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ankrd1 ( synonyms: Alrp, CARP, Crap ) | |
| Protein Name(s) | ankyrin repeat domain 1 (cardiac muscle), | |
| External Links | ||
| MGI | MGI:1097717 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_037352 |
P |
From MGI |
||
| GO:0001085 |
RNA polymerase II transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0001105 |
RNA polymerase II transcription coactivator activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0002039 |
p53 binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:86242 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3028409 |
IPI: Inferred from Physical Interaction |
RefSeq:NP_035782 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:1100225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_037352 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005667 |
transcription factor complex |
MGI:MGI:86242 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1100225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:5294542 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
MGI:MGI:86242 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_037352 |
F |
From MGI |
||
| GO:0010976 |
positive regulation of neuron projection development |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_037352 |
P |
From MGI |
||
| GO:0030016 |
myofibril |
MGI:MGI:3801259 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031432 |
titin binding |
MGI:MGI:3801259 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0031432 |
titin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031674 |
I band |
MGI:MGI:3028409 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031674 |
I band |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_037352 |
C |
From MGI |
||
| GO:0031674 |
I band |
MGI:MGI:5142381 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0035690 |
cellular response to drug |
MGI:MGI:5294542 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035994 |
response to muscle stretch |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044444 |
cytoplasmic part |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050714 |
positive regulation of protein secretion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0055008 |
cardiac muscle tissue morphogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070412 |
R-SMAD binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0071222 |
cellular response to lipopolysaccharide |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071222 |
cellular response to lipopolysaccharide |
MGI:MGI:5294542 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071260 |
cellular response to mechanical stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071347 |
cellular response to interleukin-1 |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071356 |
cellular response to tumor necrosis factor |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071560 |
cellular response to transforming growth factor beta stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000279 |
negative regulation of DNA biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Zou Y et al. (1997) CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development 124: 793-804 PubMed GONUTS page
- ↑ 2.0 2.1 Witt CC et al. (2004) Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling. J Mol Biol 336: 145-54 PubMed GONUTS page
- ↑ 3.0 3.1 Baumeister A et al. (1997) Accumulation of muscle ankyrin repeat protein transcript reveals local activation of primary myotube endcompartments during muscle morphogenesis. J Cell Biol 139: 1231-42 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Matsuura K et al. (2007) Upregulated expression of cardiac ankyrin-repeated protein in renal podocytes is associated with proteinuria severity in lupus nephritis. Hum Pathol 38: 410-9 PubMed GONUTS page
- ↑ 5.0 5.1 Hayashi C et al. (2008) Multiple molecular interactions implicate the connectin/titin N2A region as a modulating scaffold for p94/calpain 3 activity in skeletal muscle. J Biol Chem 283: 14801-14 PubMed GONUTS page
- ↑ Bang ML et al. (2001) Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies. J Cell Biol 153: 413-27 PubMed GONUTS page
