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MGI:Amot
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Amot ( synonyms: D0Kist1, Sii6 ) | |
| Protein Name(s) | angiomotin, | |
| External Links | ||
| MGI | MGI:108440 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001570 |
vasculogenesis |
MGI:MGI:2675897 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001701 |
in utero embryonic development |
MGI:MGI:2655854 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0001702 |
gastrulation with mouth forming second |
MGI:MGI:2655854 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0001725 |
stress fiber |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0001726 |
ruffle |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0003365 |
establishment of cell polarity involved in ameboidal cell migration |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0003365 |
establishment of cell polarity involved in ameboidal cell migration |
MGI:MGI:3830551 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3762993 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3830551 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q8VBX6 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:4835639 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005884 |
actin filament |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005923 |
tight junction |
MGI:MGI:3762993 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005923 |
tight junction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006935 |
chemotaxis |
MGI:MGI:2675897 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016525 |
negative regulation of angiogenesis |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2675897 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030036 |
actin cytoskeleton organization |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030139 |
endocytic vesicle |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030334 |
regulation of cell migration |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031410 |
cytoplasmic vesicle |
MGI:MGI:3762993 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0034260 |
negative regulation of GTPase activity |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0034613 |
cellular protein localization |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034613 |
cellular protein localization |
MGI:MGI:3830551 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035329 |
hippo signaling cascade |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0040019 |
positive regulation of embryonic development |
MGI:MGI:2655854 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0042074 |
cell migration involved in gastrulation |
MGI:MGI:2655854 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0043116 |
negative regulation of vascular permeability |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043532 |
angiostatin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043534 |
blood vessel endothelial cell migration |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0043536 |
positive regulation of blood vessel endothelial cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048514 |
blood vessel morphogenesis |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
||
| GO:0051056 |
regulation of small GTPase mediated signal transduction |
MGI:MGI:3719955 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2656627 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Levchenko T et al. (2003) Loss of responsiveness to chemotactic factors by deletion of the C-terminal protein interaction site of angiomotin. J Cell Sci 116: 3803-10 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Shimono A & Behringer RR (2003) Angiomotin regulates visceral endoderm movements during mouse embryogenesis. Curr Biol 13: 613-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Aase K et al. (2007) Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev 21: 2055-68 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Ernkvist M et al. (2009) The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells. Blood 113: 244-53 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Sugihara-Mizuno Y et al. (2007) Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties. Genes Cells 12: 473-86 PubMed GONUTS page
- ↑ Zheng Y et al. (2009) Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis. Circ Res 105: 260-70 PubMed GONUTS page
