Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Amelx

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Amelx ( synonyms: Amel, Amg, M100888, Rgsc888 )
Protein Name(s) amelogenin X chromosome,
External Links
MGI MGI:88005

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:1326845
PMID:11063033[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9CRG8

F

From MGI

GO:0005515

protein binding

MGI:MGI:3828400
PMID:16674683[2]

IPI: Inferred from Physical Interaction

UniProtKB:P11438

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99217

C

From MGI

GO:0005604

basement membrane

MGI:MGI:3807344
PMID:18757743[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:3828399
PMID:16674693[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007165

signal transduction

MGI:MGI:3828400
PMID:16674683[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004116

P

From MGI

GO:0008083

growth factor activity

MGI:MGI:3828399
PMID:16674693[4]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0008283

cell proliferation

MGI:MGI:3828399
PMID:16674693[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030139

endocytic vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

C

From MGI

GO:0030345

structural constituent of tooth enamel

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

F

From MGI

GO:0030345

structural constituent of tooth enamel

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99217

F

From MGI

GO:0031012

extracellular matrix

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

C

From MGI

GO:0031214

biomineral tissue development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0091

P

From MGI

GO:0034505

tooth mineralization

MGI:MGI:2149207
PMID:11406633[5]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0034505

tooth mineralization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99217

P

From MGI

GO:0042802

identical protein binding

MGI:MGI:3828411
PMID:11852235[6]

IPI: Inferred from Physical Interaction

UniProtKB:P63277

F

From MGI

GO:0042802

identical protein binding

MGI:MGI:4366712
PMID:9041053[7]

IPI: Inferred from Physical Interaction

UniProtKB:P63277

F

From MGI

GO:0042802

identical protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P63278

F

From MGI

GO:0043498

cell surface binding

MGI:MGI:3828400
PMID:16674683[2]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0046848

hydroxyapatite binding

MGI:MGI:3828411
PMID:11852235[6]

IDA: Inferred from Direct Assay

F

From MGI

GO:0070166

enamel mineralization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99217

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Paine CT et al. (1998) Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system. Connect Tissue Res 38: 257-67;discussion 295-303 PubMed GONUTS page
  2. 2.0 2.1 2.2 Deutsch D et al. (2006) Amelogenin, a major structural protein in mineralizing enamel, is also expressed in soft tissues: brain and cells of the hematopoietic system. Eur J Oral Sci 114 Suppl 1: 183-9; discussion 201-2, 381 PubMed GONUTS page
  3. Manabe R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A 105: 12849-54 PubMed GONUTS page
  4. 4.0 4.1 4.2 Zeichner-David M et al. (2006) Amelogenin and ameloblastin show growth-factor like activity in periodontal ligament cells. Eur J Oral Sci 114 Suppl 1: 244-53; discussion 254-6, 381-2 PubMed GONUTS page
  5. Gibson CW et al. (2001) Amelogenin-deficient mice display an amelogenesis imperfecta phenotype. J Biol Chem 276: 31871-5 PubMed GONUTS page
  6. 6.0 6.1 Moradian-Oldak J et al. (2002) Analysis of self-assembly and apatite binding properties of amelogenin proteins lacking the hydrophilic C-terminal. Matrix Biol 21: 197-205 PubMed GONUTS page
  7. Paine ML & Snead ML (1997) Protein interactions during assembly of the enamel organic extracellular matrix. J Bone Miner Res 12: 221-7 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox