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MGI:Alpl

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Alpl ( synonyms: Akp-2, Akp2, TNAP, TNSALP )
Protein Name(s) alkaline phosphatase, liver/bone/kidney,
External Links
MGI MGI:87983

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003006

developmental process involved in reproduction

MGI:MGI:3716023
PMID:17540358[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1354733

P

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017849
InterPro:IPR017850

F

From MGI

GO:0004035

alkaline phosphatase activity

MGI:MGI:3706740
PMID:10787428[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004035

alkaline phosphatase activity

MGI:MGI:3772269
PMID:18031938[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004035

alkaline phosphatase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P08289

F

From MGI

GO:0004035

alkaline phosphatase activity

MGI:MGI:60012
PMID:2133555[4]

ISO: Inferred from Sequence Orthology

UniProtKB:P09487

F

From MGI

GO:0004035

alkaline phosphatase activity

MGI:MGI:69442
PMID:7533563[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P08289

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3706740
PMID:10787428[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P08289

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:69442
PMID:7533563[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017849
InterPro:IPR001952
InterPro:IPR018299
InterPro:IPR017850

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016311

dephosphorylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001952
InterPro:IPR018299

P

From MGI

GO:0016311

dephosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P08289

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016791

phosphatase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001952
InterPro:IPR018299

F

From MGI

GO:0031225

anchored to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

From MGI

GO:0046677

response to antibiotic

MGI:MGI:60012
PMID:2133555[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0051384

response to glucocorticoid stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P08289

P

From MGI

GO:0071407

cellular response to organic cyclic compound

MGI:MGI:3574150
PMID:15728361[6]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kim S et al. (2007) Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation. Dev Biol 307: 314-27 PubMed GONUTS page
  2. 2.0 2.1 Garver WS et al. (2000) Localization of the murine Niemann-Pick C1 protein to two distinct intracellular compartments. J Lipid Res 41: 673-87 PubMed GONUTS page
  3. Langer D et al. (2007) The ectonucleotidases alkaline phosphatase and nucleoside triphosphate diphosphohydrolase 2 are associated with subsets of progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones. Neuroscience 150: 863-79 PubMed GONUTS page
  4. 4.0 4.1 Hahnel AC et al. (1990) Two alkaline phosphatase genes are expressed during early development in the mouse embryo. Development 110: 555-64 PubMed GONUTS page
  5. 5.0 5.1 Narisawa S et al. (1994) Stage-specific expression of alkaline phosphatase during neural development in the mouse. Dev Dyn 201: 227-35 PubMed GONUTS page
  6. Bennett CN et al. (2005) Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A 102: 3324-9 PubMed GONUTS page
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