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MGI:Alox5ap
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Alox5ap ( synonyms: arachidonate 5 lipoxygenase activating protein, Flap ) | |
| Protein Name(s) | arachidonate 5-lipoxygenase activating protein, | |
| External Links | ||
| MGI | MGI:107505 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002540 |
leukotriene production involved in inflammatory response |
MGI:MGI:3721822 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2156546 |
P |
From MGI |
||
| GO:0002540 |
leukotriene production involved in inflammatory response |
MGI:MGI:86611 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2156546 |
P |
From MGI |
||
| GO:0002675 |
positive regulation of acute inflammatory response |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3821938 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3821938 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4459044 |
PANTHER:PTHR10250 |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005792 |
microsome |
MGI:MGI:4459044 |
PANTHER:PTHR10250 |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006691 |
leukotriene metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008047 |
enzyme activator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0019370 |
leukotriene biosynthetic process |
MGI:MGI:3821938 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0019370 |
leukotriene biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019370 |
leukotriene biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019370 |
leukotriene biosynthetic process |
MGI:MGI:86611 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2156546 |
P |
From MGI |
||
| GO:0019372 |
lipoxygenase pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031965 |
nuclear membrane |
MGI:MGI:4459044 |
PANTHER:PTHR10250 |
C |
From MGI |
|||
| GO:0031965 |
nuclear membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0047485 |
protein N-terminus binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0050544 |
arachidonic acid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0070207 |
protein homotrimerization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070207 |
protein homotrimerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071277 |
cellular response to calcium ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
contributes_to |
GO:0004051 |
arachidonate 5-lipoxygenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Goulet JL et al. (2000) Genetic factors determine the contribution of leukotrienes to acute inflammatory responses. J Immunol 164: 4899-907 PubMed GONUTS page
- ↑ 2.0 2.1 Byrum RS et al. (1997) Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses. J Exp Med 185: 1065-75 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Mandal AK et al. (2008) The nuclear membrane organization of leukotriene synthesis. Proc Natl Acad Sci U S A 105: 20434-9 PubMed GONUTS page
