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MGI:Alox12

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Alox12 ( synonyms: Alox12p, P-12LO )
Protein Name(s) arachidonate 12-lipoxygenase,
External Links
MGI MGI:87998

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004052

arachidonate 12-lipoxygenase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

F

From MGI

GO:0004052

arachidonate 12-lipoxygenase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

F

From MGI

GO:0005506

iron ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001885

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005829

cytosol

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

C

From MGI

GO:0005829

cytosol

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

C

From MGI

GO:0006691

leukotriene metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001885

P

From MGI

GO:0006916

anti-apoptosis

MGI:MGI:3696513
PMID:15161019[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006916

anti-apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0006928

cellular component movement

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3696513
PMID:15161019[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0010595

positive regulation of endothelial cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0010942

positive regulation of cell death

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0016165

lipoxygenase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001885

F

From MGI

GO:0016491

oxidoreductase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

From MGI

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0223

F

From MGI

GO:0016702

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000907
InterPro:IPR013819
InterPro:IPR020834
InterPro:IPR020833

F

From MGI

GO:0019370

leukotriene biosynthetic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0434

P

From MGI

GO:0019395

fatty acid oxidation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0030307

positive regulation of cell growth

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0042383

sarcolemma

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

C

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0043280

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0045603

positive regulation of endothelial cell differentiation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0045785

positive regulation of cell adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18054

P

From MGI

GO:0045909

positive regulation of vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000907
InterPro:IPR013819
InterPro:IPR020834
InterPro:IPR020833

F

From MGI

GO:0048661

positive regulation of smooth muscle cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0051901

positive regulation of mitochondrial depolarization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001099268

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

From MGI

GO:0055114

oxidation-reduction process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000907
InterPro:IPR013819
InterPro:IPR020834
InterPro:IPR020833
InterPro:IPR001885

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ikemoto S et al. (2004) Antitumor effects of lipoxygenase inhibitors on murine bladder cancer cell line (MBT-2). Anticancer Res 24: 733-6 PubMed GONUTS page
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