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MGI:Alms1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Alms1 | |
| Protein Name(s) | Alstrom syndrome 1 homolog (human), | |
| External Links | ||
| MGI | MGI:1934606 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001678 |
cellular glucose homeostasis |
MGI:MGI:2183185 |
ISO: Inferred from Sequence Orthology |
EMBL:AJ417593 |
P |
From MGI |
||
| GO:0001736 |
establishment of planar polarity |
MGI:MGI:4867594 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0003674 |
molecular function |
MGI:MGI:2156816 |
ND: No biological Data available |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005929 |
cilium |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0969 |
C |
From MGI |
||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:3588454 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0006641 |
triglyceride metabolic process |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0007286 |
spermatid development |
MGI:MGI:3639060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3621984 |
P |
From MGI |
||
| GO:0007286 |
spermatid development |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0007605 |
sensory perception of sound |
MGI:MGI:3588454 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0007605 |
sensory perception of sound |
MGI:MGI:3639060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3621984 |
P |
From MGI |
||
| GO:0007605 |
sensory perception of sound |
MGI:MGI:4867594 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0019722 |
calcium-mediated signaling |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030728 |
ovulation |
MGI:MGI:3639060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3621984 |
P |
From MGI |
||
| GO:0036064 |
cilium basal body |
MGI:MGI:2154458 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0040015 |
negative regulation of multicellular organism growth |
MGI:MGI:3639060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3621984 |
P |
From MGI |
||
| GO:0042384 |
cilium assembly |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042384 |
cilium assembly |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0042593 |
glucose homeostasis |
MGI:MGI:3588454 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0042593 |
glucose homeostasis |
MGI:MGI:3639060 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3621984 |
P |
From MGI |
||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0045444 |
fat cell differentiation |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0045598 |
regulation of fat cell differentiation |
MGI:MGI:3588454 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0046548 |
retinal rod cell development |
MGI:MGI:3588454 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
||
| GO:0048589 |
developmental growth |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0050673 |
epithelial cell proliferation |
MGI:MGI:3698928 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3699224 |
P |
From MGI |
||
| GO:0060122 |
inner ear receptor stereocilium organization |
MGI:MGI:4867594 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3576051 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Collin GB et al. (2002) Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome. Nat Genet 31: 74-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Jagger D et al. (2011) Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell polarity. Hum Mol Genet 20: 466-81 PubMed GONUTS page
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 Li G et al. (2007) A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence. PLoS Genet 3: e8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Collin GB et al. (2005) Alms1-disrupted mice recapitulate human Alström syndrome. Hum Mol Genet 14: 2323-33 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Arsov T et al. (2006) Fat aussie--a new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Mol Endocrinol 20: 1610-22 PubMed GONUTS page
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