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MGI:Alk

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Alk ( synonyms: CD246, Tcrz )
Protein Name(s) anaplastic lymphoma kinase,
External Links
MGI MGI:103305

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0829

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008266
InterPro:IPR020635

F

From MGI

GO:0004714

transmembrane receptor protein tyrosine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UM73

F

From MGI

GO:0004714

transmembrane receptor protein tyrosine kinase activity

MGI:MGI:86124
PMID:9053841[1]

ISS: Inferred from Sequence or Structural Similarity

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005515

protein binding

MGI:MGI:2670822
PMID:12748172[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q80Z11

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002011

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UM73

C

From MGI

GO:0005887

integral to plasma membrane

MGI:MGI:86124
PMID:9053841[1]

ISS: Inferred from Sequence or Structural Similarity

C

From MGI

GO:0007165

signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UM73

P

From MGI

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002011

P

From MGI

GO:0007399

nervous system development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001162572

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016020

membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000998
InterPro:IPR002011

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UM73

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0046777

protein autophosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9UM73

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Iwahara T et al. (1997) Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene 14: 439-49 PubMed GONUTS page
  2. Ouyang T et al. (2003) Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA). J Biol Chem 278: 30028-36 PubMed GONUTS page
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