GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Akt1s1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Akt1s1 ( synonyms: Lobe, PRAS40 ) | |
| Protein Name(s) | AKT1 substrate 1 (proline-rich), | |
| External Links | ||
| MGI | MGI:1914855 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005625 |
soluble fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001099729 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001099729 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001099729 |
C |
From MGI |
||
| GO:0006469 |
negative regulation of protein kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007219 |
Notch signaling pathway |
MGI:MGI:2384376 |
ISA: Inferred from Sequence Alignment |
P |
From MGI |
|||
| GO:0032007 |
negative regulation of TOR signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001099729 |
C |
From MGI |
||
| GO:0043526 |
neuroprotection |
MGI:MGI:3693378 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0044445 |
cytosolic part |
MGI:MGI:3693378 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045792 |
negative regulation of cell size |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045884 |
regulation of survival gene product expression |
MGI:MGI:3694286 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chern JJ & Choi KW (2002) Lobe mediates Notch signaling to control domain-specific growth in the Drosophila eye disc. Development 129: 4005-13 PubMed GONUTS page
- ↑ 2.0 2.1 Saito A et al. (2004) Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor. J Neurosci 24: 1584-93 PubMed GONUTS page
- ↑ Saito A et al. (2006) Modulation of proline-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia. Stroke 37: 513-7 PubMed GONUTS page
cn |
n cont. |
prs |
