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MGI:Akr1c21
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Akr1c21 | |
| Protein Name(s) | aldo-keto reductase family 1, member C21, | |
| External Links | ||
| MGI | MGI:1924587 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004032 |
alditol:NADP+ 1-oxidoreductase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004033 |
aldo-keto reductase (NADP) activity |
MGI:MGI:2651753 |
ISA: Inferred from Sequence Alignment |
F |
From MGI |
|||
| GO:0004958 |
prostaglandin F receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005575 |
cellular component |
MGI:MGI:2156816 |
ND: No biological Data available |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0443 |
P |
From MGI |
||
| GO:0006693 |
prostaglandin metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006694 |
steroid biosynthetic process |
MGI:MGI:2651753 |
ISA: Inferred from Sequence Alignment |
P |
From MGI |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007586 |
digestion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008202 |
steroid metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016655 |
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016999 |
antibiotic metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0018636 |
phenanthrene 9,10-monooxygenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031406 |
carboxylic acid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032052 |
bile acid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
MGI:MGI:3697038 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
MGI:MGI:3714697 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0034694 |
response to prostaglandin stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042448 |
progesterone metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0047086 |
ketosteroid monooxygenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0047115 |
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051897 |
positive regulation of protein kinase B signaling cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
P |
From MGI |
||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:3697038 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:3714697 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071395 |
cellular response to jasmonic acid stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vergnes L et al. (2003) A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res 44: 503-11 PubMed GONUTS page
- ↑ 2.0 2.1 Faucher F et al. (2006) Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme. J Mol Biol 364: 747-63 PubMed GONUTS page
- ↑ 3.0 3.1 Faucher F et al. (2007) Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. J Mol Biol 369: 525-40 PubMed GONUTS page
