MGI:Aim2

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0003690	double-stranded DNA binding	MGI:MGI:3836373 PMID:19158679^[1]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0005515	protein binding	MGI:MGI:3836373 PMID:19158679^[1]	IPI: Inferred from Physical Interaction	UniProtKB:Q9EPB4	F	From MGI
	GO:0005634	nucleus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3836373 PMID:19158679^[1]	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	C	From MGI
	GO:0005739	mitochondrion	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	C	From MGI
	GO:0035458	cellular response to interferon-beta	MGI:MGI:3836373 PMID:19158679^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0035690	cellular response to drug	MGI:MGI:3836373 PMID:19158679^[1]	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	P	From MGI
	GO:0044444	cytoplasmic part	MGI:MGI:3836373 PMID:19158679^[1]	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	C	From MGI
	GO:0050702	interleukin-1 beta secretion	MGI:MGI:3836373 PMID:19158679^[1]	ISO: Inferred from Sequence Orthology	UniProtKB:O14862	P	From MGI
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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Bürckstümmer T et al. (2009) An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10: 266-72 PubMed GONUTS page

Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Aim2 ( synonyms: Ifi210, LOC383619 )
Protein Name(s)	absent in melanoma 2,
External Links
MGI	MGI:2686159