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MGI:Aicda
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Aicda ( synonyms: Aid ) | |
| Protein Name(s) | activation-induced cytidine deaminase, | |
| External Links | ||
| MGI | MGI:1342279 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004126 |
cytidine deaminase activity |
MGI:MGI:1339482 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004126 |
cytidine deaminase activity |
MGI:MGI:2656023 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0004126 |
cytidine deaminase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4946885 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3761960 |
IC: Inferred by Curator |
GO:0045190 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006397 |
mRNA processing |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0507 |
P |
From MGI |
||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0009972 |
cytidine deamination |
MGI:MGI:2656023 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0009972 |
cytidine deamination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016445 |
somatic diversification of immunoglobulins |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016814 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045190 |
isotype switching |
MGI:MGI:3761960 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0071222 |
cellular response to lipopolysaccharide |
MGI:MGI:3817382 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0080111 |
DNA demethylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090310 |
negative regulation of methylation-dependent chromatin silencing |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Muramatsu M et al. (1999) Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem 274: 18470-6 PubMed GONUTS page
- ↑ 2.0 2.1 Chaudhuri J et al. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 422: 726-30 PubMed GONUTS page
- ↑ Nowak U et al. (2011) The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA. Nat Immunol 12: 160-6 PubMed GONUTS page
- ↑ 4.0 4.1 Yan CT et al. (2007) IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 449: 478-82 PubMed GONUTS page
- ↑ de Yébenes VG et al. (2008) miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J Exp Med 205: 2199-206 PubMed GONUTS page
