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MGI:Ahcyl1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ahcyl1 ( synonyms: Ahcy-rs3, DCAL, IRBIT )
Protein Name(s) S-adenosylhomocysteine hydrolase-like 1,
External Links
MGI MGI:2385184

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004013

adenosylhomocysteinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.3.1.1

F

From MGI

GO:0004013

adenosylhomocysteinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000043
InterPro:IPR020082

F

From MGI

GO:0005515

protein binding

MGI:MGI:3652646
PMID:16769890[1]

IPI: Inferred from Physical Interaction

UniProtKB:O88343

F

From MGI

GO:0005515

protein binding

MGI:MGI:3848108
PMID:19224921[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9D824

F

From MGI

GO:0005622

intracellular

MGI:MGI:3848108
PMID:19224921[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0006378

mRNA polyadenylation

MGI:MGI:3848108
PMID:19224921[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006611

protein export from nucleus

MGI:MGI:3848108
PMID:19224921[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006730

one-carbon metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0554

P

From MGI

GO:0006730

one-carbon metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000043
InterPro:IPR020082

P

From MGI

GO:0010765

positive regulation of sodium ion transport

MGI:MGI:3652646
PMID:16769890[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1927555

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0031440

regulation of mRNA 3'-end processing

MGI:MGI:3848108
PMID:19224921[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032412

regulation of ion transmembrane transporter activity

MGI:MGI:3652646
PMID:16769890[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1927555

P

From MGI

GO:0044070

regulation of anion transport

MGI:MGI:3831619
PMID:19033647[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:1927555
MGI:MGI:88388

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Shirakabe K et al. (2006) IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1). Proc Natl Acad Sci U S A 103: 9542-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Kiefer H et al. (2009) Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation. J Biol Chem 284: 10694-705 PubMed GONUTS page
  3. Yang D et al. (2009) IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J Clin Invest 119: 193-202 PubMed GONUTS page
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