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MGI:Agtr1b

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Agtr1b ( synonyms: Agtr-1b, Angtr-1b, AT1B )
Protein Name(s) angiotensin II receptor, type 1b,
External Links
MGI MGI:87965

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001568

blood vessel development

MGI:MGI:1196814
PMID:9466969[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87964

P

From MGI

GO:0001596

angiotensin type I receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

F

From MGI

GO:0001596

angiotensin type I receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

F

From MGI

GO:0001822

kidney development

MGI:MGI:1196814
PMID:9466969[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87965

P

From MGI

GO:0001822

kidney development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0001991

regulation of systemic arterial blood pressure by circulatory renin-angiotensin

MGI:MGI:1196814
PMID:9466969[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87964

P

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

From MGI

GO:0004945

angiotensin type II receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

F

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

C

From MGI

GO:0006954

inflammatory response

MGI:MGI:3844151
PMID:19404405[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:87964
MGI:MGI:87966

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0007266

Rho protein signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0010698

acetyltransferase activator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

F

From MGI

GO:0010873

positive regulation of cholesterol esterification

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0012506

vesicle membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR000190
InterPro:IPR000248

C

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

C

From MGI

GO:0017046

peptide hormone binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

F

From MGI

GO:0019229

regulation of vasoconstriction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0019722

calcium-mediated signaling

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0031711

bradykinin receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

F

From MGI

GO:0031983

vesicle lumen

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

C

From MGI

GO:0032270

positive regulation of cellular protein metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0032430

positive regulation of phospholipase A2 activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0042756

drinking behavior

MGI:MGI:3608656
PMID:10880053[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:87964

P

From MGI

GO:0042756

drinking behavior

MGI:MGI:3608656
PMID:10880053[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2157020

P

From MGI

GO:0043621

protein self-association

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

F

From MGI

GO:0043627

response to estrogen stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

F

From MGI

GO:0051482

elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0060326

cell chemotaxis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P30556

P

From MGI

GO:0071549

cellular response to dexamethasone stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

P

From MGI

GO:0090190

positive regulation of branching involved in ureteric bud morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29089

P

From MGI

NOT

GO:0002035

brain renin-angiotensin system

MGI:MGI:3608656
PMID:10880053[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2157020

P

From MGI

NOT

GO:0043524

negative regulation of neuron apoptotic process

MGI:MGI:2385817
PMID:9310306[4]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Tsuchida S et al. (1998) Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes. J Clin Invest 101: 755-60 PubMed GONUTS page
  2. Esteban V et al. (2009) Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. PLoS One 4: e5406 PubMed GONUTS page
  3. 3.0 3.1 3.2 Davisson RL et al. (2000) Divergent functions of angiotensin II receptor isoforms in the brain. J Clin Invest 106: 103-6 PubMed GONUTS page
  4. Kakinuma Y et al. (1997) Anti-apoptotic action of angiotensin fragments to neuronal cells from angiotensinogen knock-out mice. Neurosci Lett 232: 167-70 PubMed GONUTS page
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