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MGI:Adrb3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Adrb3 ( synonyms: Adrb-3, beta 3-AR, Beta-3 adrenoceptor, Beta-3 AR, beta3-adrenergic receptor ) | |
| Protein Name(s) | adrenergic receptor, beta 3, | |
| External Links | ||
| MGI | MGI:87939 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002024 |
diet induced thermogenesis |
MGI:MGI:2387786 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0002025 |
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure |
MGI:MGI:1338641 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From MGI |
||
| GO:0004935 |
adrenergic receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004939 |
beta-adrenergic receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:72815 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:72815 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007189 |
activation of adenylate cyclase activity by G-protein signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007189 |
activation of adenylate cyclase activity by G-protein signaling pathway |
MGI:MGI:72815 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007190 |
activation of adenylate cyclase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009409 |
response to cold |
MGI:MGI:2387786 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0009409 |
response to cold |
MGI:MGI:2388907 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0015052 |
beta3-adrenergic receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0031649 |
heat generation |
MGI:MGI:2387786 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0031699 |
beta-3 adrenergic receptor binding |
MGI:MGI:1097308 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0031699 |
beta-3 adrenergic receptor binding |
MGI:MGI:72815 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0040015 |
negative regulation of multicellular organism growth |
MGI:MGI:2388907 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0042755 |
eating behavior |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043235 |
receptor complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043410 |
positive regulation of MAPK cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050873 |
brown fat cell differentiation |
MGI:MGI:2388907 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87937 |
P |
From MGI |
||
| GO:0051379 |
epinephrine binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051380 |
norepinephrine binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0071875 |
adrenergic receptor signaling pathway |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0071875 |
adrenergic receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Bachman ES et al. (2002) betaAR signaling required for diet-induced thermogenesis and obesity resistance. Science 297: 843-5 PubMed GONUTS page
- ↑ Rohrer DK et al. (1999) Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors. J Biol Chem 274: 16701-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Rohlfs EM et al. (1995) Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines. J Biol Chem 270: 10723-32 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Jimenez M et al. (2002) Beta(1)/beta(2)/beta(3)-adrenoceptor knockout mice are obese and cold-sensitive but have normal lipolytic responses to fasting. FEBS Lett 530: 37-40 PubMed GONUTS page
- ↑ Hadri KE et al. (1997) Differential regulation by tumor necrosis factor-alpha of beta1-, beta2-, and beta3-adrenoreceptor gene expression in 3T3-F442A adipocytes. J Biol Chem 272: 24514-21 PubMed GONUTS page
