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MGI:Adora1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Adora1 ( synonyms: A1-AR, A1AR, A1R, AA1R, Ri )
Protein Name(s) adenosine A1 receptor,
External Links
MGI MGI:99401

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000186

activation of MAPKK activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0001609

G-protein coupled adenosine receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0001659

temperature homeostasis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0001664

G-protein coupled receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0001666

response to hypoxia

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0001883

purine nucleoside binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0001973

adenosine receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0002087

regulation of respiratory gaseous exchange by neurological system process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0002674

negative regulation of acute inflammatory response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0002686

negative regulation of leukocyte migration

MGI:MGI:3525377
PMID:15630442[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87916

P

From MGI

GO:0002793

positive regulation of peptide secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0003093

regulation of glomerular filtration

MGI:MGI:3606554
PMID:15283758[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388340

P

From MGI

GO:0004629

phospholipase C activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0006612

protein targeting to membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0012505

endomembrane system

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0014050

negative regulation of glutamate secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0014069

postsynaptic density

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR001068
InterPro:IPR001634

C

From MGI

GO:0016042

lipid catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0016323

basolateral plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0030673

axolemma

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0031683

G-protein beta/gamma-subunit complex binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0032229

negative regulation of synaptic transmission, GABAergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0032244

positive regulation of nucleoside transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0032279

asymmetric synapse

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0032795

heterotrimeric G-protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0032900

negative regulation of neurotrophin production

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0035307

positive regulation of protein dephosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0035814

negative regulation of renal sodium excretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0042323

negative regulation of circadian sleep/wake cycle, non-REM sleep

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0042734

presynaptic membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0043025

neuronal cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0043195

terminal button

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0043268

positive regulation of potassium ion transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0044297

cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0045211

postsynaptic membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0045741

positive regulation of epidermal growth factor-activated receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0045776

negative regulation of blood pressure

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0045777

positive regulation of blood pressure

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0045822

negative regulation of heart contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0045908

negative regulation of vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0046888

negative regulation of hormone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

F

From MGI

GO:0048167

regulation of synaptic plasticity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0048786

presynaptic active zone

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

C

From MGI

GO:0050728

negative regulation of inflammatory response

MGI:MGI:3525377
PMID:15630442[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87916

P

From MGI

GO:0050890

cognition

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0050965

detection of temperature stimulus involved in sensory perception of pain

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0050995

negative regulation of lipid catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0051967

negative regulation of synaptic transmission, glutamatergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0055117

regulation of cardiac muscle contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0055118

negative regulation of cardiac muscle contraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0060079

regulation of excitatory postsynaptic membrane potential

MGI:MGI:3708428
PMID:17428973[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060079

regulation of excitatory postsynaptic membrane potential

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0060087

relaxation of vascular smooth muscle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

GO:0070256

negative regulation of mucus secretion

MGI:MGI:3525377
PMID:15630442[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:87916

P

From MGI

NOT

GO:0032229

negative regulation of synaptic transmission, GABAergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI

NOT

GO:0042312

regulation of vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O08766

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Sun CX et al. (2005) A protective role for the A1 adenosine receptor in adenosine-dependent pulmonary injury. J Clin Invest 115: 35-43 PubMed GONUTS page
  2. Hashimoto S et al. (2004) Compensation of proximal tubule malabsorption in AQP1-deficient mice without TGF-mediated reduction of GFR. Acta Physiol Scand 181: 455-62 PubMed GONUTS page
  3. Rebola N et al. (2007) Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses. J Neurosci 27: 3987-93 PubMed GONUTS page
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