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MGI:Adh5
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Adh5 ( synonyms: Adh-5, Adh3, GSNOR, S-nitrosoglutathione reductase ) | |
| Protein Name(s) | alcohol dehydrogenase 5 (class III), chi polypeptide, | |
| External Links | ||
| MGI | MGI:87929 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0001523 |
retinoid metabolic process |
MGI:MGI:2180234 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180101 |
P |
From MGI |
||
| GO:0003016 |
respiratory system process |
MGI:MGI:3616157 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
P |
From MGI |
||
| GO:0004022 |
alcohol dehydrogenase (NAD) activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004022 |
alcohol dehydrogenase (NAD) activity |
MGI:MGI:56327 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005504 |
fatty acid binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:56327 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006068 |
ethanol catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006069 |
ethanol oxidation |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR013149 |
F |
From MGI |
||
| GO:0018119 |
peptidyl-cysteine S-nitrosylation |
MGI:MGI:3032823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
P |
From MGI |
||
| GO:0018467 |
formaldehyde dehydrogenase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032496 |
response to lipopolysaccharide |
MGI:MGI:3032823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:56327 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0045777 |
positive regulation of blood pressure |
MGI:MGI:3032823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
P |
From MGI |
||
| GO:0046294 |
formaldehyde catabolic process |
MGI:MGI:1338643 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180100 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051409 |
response to nitrosative stress |
MGI:MGI:3032823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
P |
From MGI |
||
| GO:0051775 |
response to redox state |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051903 |
S-(hydroxymethyl)glutathione dehydrogenase activity |
MGI:MGI:3616157 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3033711 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Molotkov A et al. (2002) Excessive vitamin A toxicity in mice genetically deficient in either alcohol dehydrogenase Adh1 or Adh3. Eur J Biochem 269: 2607-12 PubMed GONUTS page
- ↑ 2.0 2.1 Que LG et al. (2005) Protection from experimental asthma by an endogenous bronchodilator. Science 308: 1618-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Algar EM & Holmes RS (1985) Mouse mitochondrial aldehyde dehydrogenase isozymes: purification and molecular properties. Int J Biochem 17: 51-60 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Liu L et al. (2004) Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell 116: 617-28 PubMed GONUTS page
- ↑ Deltour L et al. (1999) Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid. J Biol Chem 274: 16796-801 PubMed GONUTS page
