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MGI:Adcyap1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Adcyap1 ( synonyms: PACAP )
Protein Name(s) adenylate cyclase activating polypeptide 1,
External Links
MGI MGI:105094

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001541

ovarian follicle development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0001662

behavioral fear response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0001821

histamine secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0002865

negative regulation of acute inflammatory response to antigenic stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0002878

negative regulation of acute inflammatory response to non-antigenic stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0005057

receptor signaling protein activity

MGI:MGI:1277003
PMID:9729410[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005057

receptor signaling protein activity

MGI:MGI:2450214
PMID:12473665[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005102

receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

F

From MGI

GO:0005179

hormone activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0372

F

From MGI

GO:0005179

hormone activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000532

F

From MGI

GO:0005184

neuropeptide hormone activity

MGI:MGI:1277003
PMID:9729410[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000532

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

C

From MGI

GO:0007190

activation of adenylate cyclase activity

MGI:MGI:1277003
PMID:9729410[1]

TAS: Traceable Author Statement

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0007218

neuropeptide signaling pathway

MGI:MGI:1277003
PMID:9729410[1]

TAS: Traceable Author Statement

P

From MGI

GO:0008277

regulation of G-protein coupled receptor protein signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0010579

positive regulation of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0010579

positive regulation of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0016521

pituitary adenylate cyclase activating polypeptide activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

F

From MGI

GO:0016521

pituitary adenylate cyclase activating polypeptide activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

F

From MGI

GO:0019233

sensory perception of pain

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0030819

positive regulation of cAMP biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0031858

pituitary adenylate cyclase-activating polypeptide receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

F

From MGI

GO:0032755

positive regulation of interleukin-6 production

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0032880

regulation of protein localization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0032880

regulation of protein localization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

P

From MGI

GO:0034259

negative regulation of Rho GTPase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0043195

terminal button

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

C

From MGI

GO:0043267

negative regulation of potassium ion transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0045768

positive regulation of anti-apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0045786

negative regulation of cell cycle

MGI:MGI:2429375
PMID:12417650[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045909

positive regulation of vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0046034

ATP metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0051428

peptide hormone receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18509

F

From MGI

GO:0051968

positive regulation of synaptic transmission, glutamatergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0060078

regulation of postsynaptic membrane potential

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0060124

positive regulation of growth hormone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0060253

negative regulation of glial cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0070445

regulation of oligodendrocyte progenitor proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI

GO:0090274

positive regulation of somatostatin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P13589

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Sheward WJ et al. (1998) Expression of PACAP, and PACAP type 1 (PAC1) receptor mRNA during development of the mouse embryo. Brain Res Dev Brain Res 109: 245-53 PubMed GONUTS page
  2. Bouschet T et al. (2003) Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells. J Biol Chem 278: 4778-85 PubMed GONUTS page
  3. Nicot A et al. (2002) Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation. J Neurosci 22: 9244-54 PubMed GONUTS page
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