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MGI:Adamts20

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Adamts20 ( synonyms: ADAMTS-20, bt )
Protein Name(s) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20,
External Links
MGI MGI:2660628

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004175

endopeptidase activity

MGI:MGI:3778519
PMID:18454205[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:2656109
PMID:12562771[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013273

C

From MGI

GO:0005615

extracellular space

MGI:MGI:3778519
PMID:18454205[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006508

proteolysis

MGI:MGI:2656109
PMID:12562771[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006508

proteolysis

MGI:MGI:3778519
PMID:18454205[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013273

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

From MGI

GO:0008237

metallopeptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0482

F

From MGI

GO:0008237

metallopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013273

F

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR012314
InterPro:IPR013273
InterPro:IPR002870

F

From MGI

GO:0009967

positive regulation of signal transduction

MGI:MGI:3778519
PMID:18454205[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3766915

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0030198

extracellular matrix organization

MGI:MGI:3778519
PMID:18454205[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR010294

C

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:3778519
PMID:18454205[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3766915

P

From MGI

GO:0045636

positive regulation of melanocyte differentiation

MGI:MGI:3778519
PMID:18454205[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1916320

P

From MGI

GO:0045636

positive regulation of melanocyte differentiation

MGI:MGI:3778519
PMID:18454205[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3766915

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048070

regulation of developmental pigmentation

MGI:MGI:3778519
PMID:18454205[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1916320

P

From MGI

GO:0048070

regulation of developmental pigmentation

MGI:MGI:3778519
PMID:18454205[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:96677

P

From MGI

GO:0048070

regulation of developmental pigmentation

MGI:MGI:3778519
PMID:18454205[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3766915

P

From MGI

GO:0048070

regulation of developmental pigmentation

MGI:MGI:60945
PMID:14138974[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2675831

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Silver DL et al. (2008) The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet 4: e1000003 PubMed GONUTS page
  2. 2.0 2.1 Llamazares M et al. (2003) Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain. J Biol Chem 278: 13382-9 PubMed GONUTS page
  3. MAYER TC & MALTBY EL (1964) AN EXPERIMENTAL INVESTIGATION OF PATTERN DEVELOPMENT IN LETHAL SPOTTING AND BELTED MOUSE EMBRYOS. Dev Biol 22: 269-86 PubMed GONUTS page
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