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MGI:Adamts2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Adamts2 ( synonyms: a disintegrin and metalloproteinase with thrombospondin repeats, ADAM-TS2, hPCPNI, procollagen N-proteinase ) | |
| Protein Name(s) | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2, | |
| External Links | ||
| MGI | MGI:1347356 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004222 |
metalloendopeptidase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0272 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006508 |
proteolysis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
P |
From MGI |
||
| GO:0006508 |
proteolysis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007229 |
integrin-mediated signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0401 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:1934098 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2388161 |
P |
From MGI |
||
| GO:0008233 |
peptidase activity |
MGI:MGI:3621082 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008237 |
metallopeptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0482 |
F |
From MGI |
||
| GO:0008237 |
metallopeptidase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016485 |
protein processing |
MGI:MGI:3621082 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2388161 |
P |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0030199 |
collagen fibril organization |
MGI:MGI:3621082 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2388161 |
P |
From MGI |
||
| GO:0030324 |
lung development |
MGI:MGI:3621082 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2388161 |
P |
From MGI |
||
| GO:0030574 |
collagen catabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0177 |
P |
From MGI |
||
| GO:0031012 |
extracellular matrix |
MGI:MGI:3621082 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043588 |
skin development |
MGI:MGI:1934098 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2388161 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Li SW et al. (2001) Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility. Biochem J 355: 271-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Le Goff C et al. (2006) Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis. Development 133: 1587-96 PubMed GONUTS page