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MGI:Adamts2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Adamts2 ( synonyms: a disintegrin and metalloproteinase with thrombospondin repeats, ADAM-TS2, hPCPNI, procollagen N-proteinase )
Protein Name(s) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2,
External Links
MGI MGI:1347356

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004222

metalloendopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR010294
InterPro:IPR001590
InterPro:IPR002870

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

From MGI

GO:0005578

proteinaceous extracellular matrix

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013275
InterPro:IPR013273

C

From MGI

GO:0006508

proteolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001590
InterPro:IPR002870

P

From MGI

GO:0007229

integrin-mediated signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0401

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:1934098
PMID:11284712[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388161

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:3621082
PMID:16556917[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0008237

metallopeptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0482

F

From MGI

GO:0008237

metallopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013275
InterPro:IPR013273

F

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013275
InterPro:IPR013273
InterPro:IPR002870

F

From MGI

GO:0016485

protein processing

MGI:MGI:3621082
PMID:16556917[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388161

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0030199

collagen fibril organization

MGI:MGI:3621082
PMID:16556917[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388161

P

From MGI

GO:0030324

lung development

MGI:MGI:3621082
PMID:16556917[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388161

P

From MGI

GO:0030574

collagen catabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0177

P

From MGI

GO:0031012

extracellular matrix

MGI:MGI:3621082
PMID:16556917[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043588

skin development

MGI:MGI:1934098
PMID:11284712[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2388161

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Li SW et al. (2001) Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility. Biochem J 355: 271-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Le Goff C et al. (2006) Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis. Development 133: 1587-96 PubMed GONUTS page
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