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MGI:Adam2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Adam2 ( synonyms: fertilin beta, Ftnb, Ph30-beta )
Protein Name(s) a disintegrin and metallopeptidase domain 2,
External Links
MGI MGI:1340894

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001669

acrosomal vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63202

C

From MGI

GO:0004222

metalloendopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006586
InterPro:IPR001590
InterPro:IPR002870

F

From MGI

GO:0005515

protein binding

MGI:MGI:3052285
PMID:15194697[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q60813
UniProtKB:Q8R534

F

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006586
InterPro:IPR001590
InterPro:IPR002870

P

From MGI

GO:0007155

cell adhesion

MGI:MGI:4849299
PMID:21060781[2]

IGI: Inferred from Genetic Interaction

UniProtKB:Q13797

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002870

F

From MGI

GO:0008542

visual learning

MGI:MGI:3620328
PMID:16504143[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3625523

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030534

adult behavior

MGI:MGI:3620328
PMID:16504143[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3625523

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Nishimura H et al. (2004) Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface. J Biol Chem 279: 34957-62 PubMed GONUTS page
  2. Desiderio UV et al. (2010) ADAM2 interactions with mouse eggs and cell lines expressing α4/α9 (ITGA4/ITGA9) integrins: implications for integrin-based adhesion and fertilization. PLoS One 5: e13744 PubMed GONUTS page
  3. 3.0 3.1 Takahashi E et al. (2006) Deficits in spatial learning and motor coordination in ADAM11-deficient mice. BMC Neurosci 7: 19 PubMed GONUTS page
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