Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Acta2

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Acta2 ( synonyms: a-SMA, Actvs, alphaSMA, SMalphaA )
Protein Name(s) actin, alpha 2, smooth muscle, aorta,
External Links
MGI MGI:87909

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004001

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:2429331
PMID:12355421[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P62736

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3759000
PMID:17717145[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P62736

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:5052199
PMID:21708977[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:3688953
PMID:16989802[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0008217

regulation of blood pressure

MGI:MGI:3665239
PMID:11053242[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3665248

P

From MGI

GO:0014829

vascular smooth muscle contraction

MGI:MGI:3665239
PMID:11053242[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3665248

P

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:3761040
PMID:17882221[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:81256
PMID:8616889[7]

ISO: Inferred from Sequence Orthology

UniProtKB:P62738

C

From MGI

GO:0030485

smooth muscle contractile fiber

MGI:MGI:3794929
PMID:18332105[8]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ju WK & Neufeld AH (2002) Cellular localization of cyclooxygenase-1 and cyclooxygenase-2 in the normal mouse, rat, and human retina. J Comp Neurol 452: 392-9 PubMed GONUTS page
  2. Zhang H et al. (2007) Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. Am J Pathol 171: 1113-26 PubMed GONUTS page
  3. Crippa S et al. (2011) miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J Cell Biol 193: 1197-212 PubMed GONUTS page
  4. De Langhe SP et al. (2006) Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 299: 52-62 PubMed GONUTS page
  5. 5.0 5.1 Schildmeyer LA et al. (2000) Impaired vascular contractility and blood pressure homeostasis in the smooth muscle alpha-actin null mouse. FASEB J 14: 2213-20 PubMed GONUTS page
  6. Seandel M et al. (2007) Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature 449: 346-50 PubMed GONUTS page
  7. Shah NM et al. (1996) Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell 85: 331-43 PubMed GONUTS page
  8. Ogata T et al. (2008) MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol 28: 3424-36 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox