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MGI:Acr
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Acr ( synonyms: preproacrosin ) | |
| Protein Name(s) | acrosin prepropeptide, | |
| External Links | ||
| MGI | MGI:87884 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001669 |
acrosomal vesicle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0001669 |
acrosomal vesicle |
MGI:MGI:69848 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0002077 |
acrosome matrix dispersal |
MGI:MGI:3808932 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004252 |
serine-type endopeptidase activity |
MGI:MGI:3687913 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004252 |
serine-type endopeptidase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2154647 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005537 |
mannose binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005798 |
Golgi-associated vesicle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006508 |
proteolysis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0645 |
P |
From MGI |
||
| GO:0006508 |
proteolysis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007190 |
activation of adenylate cyclase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007338 |
single fertilization |
MGI:MGI:3577815 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007339 |
binding of sperm to zona pellucida |
MGI:MGI:3577815 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96945 |
P |
From MGI |
||
| GO:0007339 |
binding of sperm to zona pellucida |
MGI:MGI:3808932 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007340 |
acrosome reaction |
MGI:MGI:3687913 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0007340 |
acrosome reaction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007341 |
penetration of zona pellucida |
MGI:MGI:3042304 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96945 |
P |
From MGI |
||
| GO:0007341 |
penetration of zona pellucida |
MGI:MGI:69844 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180087 |
P |
From MGI |
||
| GO:0007341 |
penetration of zona pellucida |
MGI:MGI:86042 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429958 |
P |
From MGI |
||
| GO:0008233 |
peptidase activity |
MGI:MGI:69844 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180087 |
F |
From MGI |
||
| GO:0008233 |
peptidase activity |
MGI:MGI:86042 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429958 |
F |
From MGI |
||
| GO:0008236 |
serine-type peptidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0720 |
F |
From MGI |
||
| GO:0009607 |
response to biotic stimulus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0043159 |
acrosomal matrix |
MGI:MGI:3687913 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0048545 |
response to steroid hormone stimulus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nayernia K et al. (1994) Functional and molecular characterization of the transcriptional regulatory region of the proacrosin gene. J Biol Chem 269: 32181-6 PubMed GONUTS page
- ↑ 2.0 2.1 Turner LM et al. (2008) Comparative analysis of testis protein evolution in rodents. Genetics 179: 2075-89 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Honda A et al. (2002) Role of acrosomal matrix proteases in sperm-zona pellucida interactions. Hum Reprod Update 8: 405-12 PubMed GONUTS page
- ↑ Howes E et al. (2001) Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization. J Cell Sci 114: 4127-36 PubMed GONUTS page
- ↑ 5.0 5.1 Nayernia K et al. (2005) Triple knockouts reveal gene interactions affecting fertility of male mice. Mol Reprod Dev 70: 406-16 PubMed GONUTS page
- ↑ Nayernia K et al. (2003) Synergistic effects of germ cell expressed genes on male fertility in mice. Cytogenet Genome Res 103: 314-20 PubMed GONUTS page
- ↑ 7.0 7.1 Baba T et al. (1994) Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization. J Biol Chem 269: 31845-9 PubMed GONUTS page
- ↑ 8.0 8.1 Adham IM et al. (1997) Spermatozoa lacking acrosin protein show delayed fertilization. Mol Reprod Dev 46: 370-6 PubMed GONUTS page
