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MGI:Acly

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Acly
Protein Name(s) ATP citrate lyase,
External Links
MGI MGI:103251

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017440
InterPro:IPR005810
InterPro:IPR005811

F

From MGI

GO:0003878

ATP citrate synthase activity

MGI:MGI:1271047
PMID:1371749[1]

TAS: Traceable Author Statement

F

From MGI

GO:0003878

ATP citrate synthase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P16638

F

From MGI

GO:0004775

succinate-CoA ligase (ADP-forming) activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017440

F

From MGI

GO:0005515

protein binding

MGI:MGI:3688344
PMID:15102471[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q8CFN5-4

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013816

F

From MGI

GO:0005622

intracellular

MGI:MGI:1271047
PMID:1371749[1]

TAS: Traceable Author Statement

C

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P16638

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4E3P0

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4E3P0

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4E3P0

C

From MGI

GO:0006084

acetyl-CoA metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P16638

P

From MGI

GO:0006085

acetyl-CoA biosynthetic process

MGI:MGI:1271047
PMID:1371749[1]

TAS: Traceable Author Statement

P

From MGI

GO:0006101

citrate metabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P16638

P

From MGI

GO:0006633

fatty acid biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P16638

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017440
InterPro:IPR005810
InterPro:IPR005811

P

From MGI

GO:0008610

lipid biosynthetic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0444

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016829

lyase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

From MGI

GO:0044262

cellular carbohydrate metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR014608
InterPro:IPR016142
InterPro:IPR016143
InterPro:IPR002020
InterPro:IPR016141

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016142
InterPro:IPR016143
InterPro:IPR002020
InterPro:IPR016141

F

From MGI

GO:0048037

cofactor binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003781

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Elshourbagy NA et al. (1992) Cloning and expression of a human ATP-citrate lyase cDNA. Eur J Biochem 204: 491-9 PubMed GONUTS page
  2. Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
  3. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
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