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MGI:Acan
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Acan ( synonyms: Agc1, Cspg1 ) | |
| Protein Name(s) | aggrecan, | |
| External Links | ||
| MGI | MGI:99602 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001502 |
cartilage condensation |
MGI:MGI:2664273 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856465 |
P |
From MGI |
||
| GO:0002063 |
chondrocyte development |
MGI:MGI:1270958 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856465 |
P |
From MGI |
||
| GO:0005509 |
calcium ion binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3607633 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5294318 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005540 |
hyaluronic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:2679405 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005604 |
basement membrane |
MGI:MGI:3607633 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0030166 |
proteoglycan biosynthetic process |
MGI:MGI:2664273 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856465 |
P |
From MGI |
||
| GO:0030199 |
collagen fibril organization |
MGI:MGI:2664273 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856465 |
P |
From MGI |
||
| GO:0030246 |
carbohydrate binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030336 |
negative regulation of cell migration |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031012 |
extracellular matrix |
MGI:MGI:3767479 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0072534 |
perineuronal net |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Seegmiller RE et al. (1988) Histochemical, immunofluorescence, and ultrastructural differences in fetal cartilage among three genetically distinct chondrodystrophic mice. Teratology 38: 579-92 PubMed GONUTS page
- ↑ Wai AW et al. (1998) Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant. Dev Genet 22: 349-58 PubMed GONUTS page
- ↑ 3.0 3.1 Lee NV et al. (2005) Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem 280: 34796-804 PubMed GONUTS page
- ↑ Liu Y et al. (1997) Overexpression of a single helix-loop-helix-type transcription factor, scleraxis, enhances aggrecan gene expression in osteoblastic osteosarcoma ROS17/2.8 cells. J Biol Chem 272: 29880-5 PubMed GONUTS page
- ↑ Shibata S et al. (2003) In situ hybridization and immunohistochemistry of versican, aggrecan and link protein, and histochemistry of hyaluronan in the developing mouse limb bud cartilage. J Anat 203: 425-32 PubMed GONUTS page
- ↑ Klüppel M et al. (2005) Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis. Development 132: 3989-4003 PubMed GONUTS page
bc |
c cont.eh |
np |
