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MGI:Abhd5
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Abhd5 ( synonyms: CGI-58, IECN5, NCIE2 ) | |
| Protein Name(s) | abhydrolase domain containing 5, | |
| External Links | ||
| MGI | MGI:1914719 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003841 |
1-acylglycerol-3-phosphate O-acyltransferase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3769941 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005811 |
lipid particle |
MGI:MGI:3850312 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:3850312 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006629 |
lipid metabolic process |
MGI:MGI:3487148 |
ISA: Inferred from Sequence Alignment |
P |
From MGI |
|||
| GO:0006631 |
fatty acid metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0276 |
P |
From MGI |
||
| GO:0006654 |
phosphatidic acid biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008654 |
phospholipid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0594 |
P |
From MGI |
||
| GO:0010891 |
negative regulation of sequestering of triglyceride |
MGI:MGI:3769941 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010891 |
negative regulation of sequestering of triglyceride |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010898 |
positive regulation of triglyceride catabolic process |
MGI:MGI:3769941 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0010898 |
positive regulation of triglyceride catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016746 |
transferase activity, transferring acyl groups |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0012 |
F |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0042171 |
lysophosphatidic acid acyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051006 |
positive regulation of lipoprotein lipase activity |
MGI:MGI:3697284 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
|
NOT |
GO:0004806 |
triglyceride lipase activity |
MGI:MGI:3769941 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Lass A et al. (2006) Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab 3: 309-19 PubMed GONUTS page
- ↑ 2.0 2.1 Ghosh AK et al. (2008) CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid. J Biol Chem 283: 24525-33 PubMed GONUTS page
- ↑ Yamaguchi T et al. (2004) CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome. J Biol Chem 279: 30490-7 PubMed GONUTS page
- ↑ Schweiger M et al. (2006) Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Biol Chem 281: 40236-41 PubMed GONUTS page
