![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Aars
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Aars | |
| Protein Name(s) | alanyl-tRNA synthetase, | |
| External Links | ||
| MGI | MGI:2384560 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000049 |
tRNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002318 |
F |
From MGI |
||
| GO:0001942 |
hair follicle development |
MGI:MGI:3639059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0002161 |
aminoacyl-tRNA editing activity |
MGI:MGI:4457227 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0004812 |
aminoacyl-tRNA ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0030 |
F |
From MGI |
||
| GO:0004813 |
alanine-tRNA ligase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006400 |
tRNA modification |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006412 |
translation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0648 |
P |
From MGI |
||
| GO:0006419 |
alanyl-tRNA aminoacylation |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0006419 |
alanyl-tRNA aminoacylation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006457 |
protein folding |
MGI:MGI:3639059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0016597 |
amino acid binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0016876 |
ligase activity, forming aminoacyl-tRNA and related compounds |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0021680 |
cerebellar Purkinje cell layer development |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0030968 |
endoplasmic reticulum unfolded protein response |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0034620 |
cellular response to unfolded protein |
MGI:MGI:3652460 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0043039 |
tRNA aminoacylation |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0043200 |
response to amino acid stimulus |
MGI:MGI:3639059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0043588 |
skin development |
MGI:MGI:3639059 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0050885 |
neuromuscular process controlling balance |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
||
| GO:0050905 |
neuromuscular process |
MGI:MGI:3640843 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3618596 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Tsukiyama K et al. (2006) Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. Mol Endocrinol 20: 1644-51 PubMed GONUTS page
- ↑ Guo M et al. (2009) Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature 462: 808-12 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Lee JW et al. (2006) Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature 443: 50-5 PubMed GONUTS page
- ↑ Mizoguchi A et al. (2003) Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation. Int Immunol 15: 97-108 PubMed GONUTS page