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MGI:Aars

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Aars
Protein Name(s) alanyl-tRNA synthetase,
External Links
MGI MGI:2384560

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000049

tRNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000166

nucleotide binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002318
InterPro:IPR018162
InterPro:IPR018164
InterPro:IPR018163

F

From MGI

GO:0001942

hair follicle development

MGI:MGI:3639059
PMID:16469773[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0002161

aminoacyl-tRNA editing activity

MGI:MGI:4457227
PMID:20010690[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003676

nucleic acid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018165
InterPro:IPR003156

F

From MGI

GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0004812

aminoacyl-tRNA ligase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0030

F

From MGI

GO:0004813

alanine-tRNA ligase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

C

From MGI

GO:0006400

tRNA modification

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006412

translation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0648

P

From MGI

GO:0006419

alanyl-tRNA aminoacylation

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0006419

alanyl-tRNA aminoacylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

P

From MGI

GO:0006457

protein folding

MGI:MGI:3639059
PMID:16469773[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0016597

amino acid binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P50475

F

From MGI

GO:0016874

ligase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

From MGI

GO:0016876

ligase activity, forming aminoacyl-tRNA and related compounds

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR012947

F

From MGI

GO:0021680

cerebellar Purkinje cell layer development

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0030968

endoplasmic reticulum unfolded protein response

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0034620

cellular response to unfolded protein

MGI:MGI:3652460
PMID:12502730[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0043039

tRNA aminoacylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR012947

P

From MGI

GO:0043200

response to amino acid stimulus

MGI:MGI:3639059
PMID:16469773[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0043524

negative regulation of neuron apoptotic process

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0043588

skin development

MGI:MGI:3639059
PMID:16469773[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050885

neuromuscular process controlling balance

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI

GO:0050905

neuromuscular process

MGI:MGI:3640843
PMID:16906134[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3618596

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Tsukiyama K et al. (2006) Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. Mol Endocrinol 20: 1644-51 PubMed GONUTS page
  2. Guo M et al. (2009) Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature 462: 808-12 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Lee JW et al. (2006) Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature 443: 50-5 PubMed GONUTS page
  4. Mizoguchi A et al. (2003) Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation. Int Immunol 15: 97-108 PubMed GONUTS page
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