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MGI:A2m

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) A2m ( synonyms: A2mp )
Protein Name(s) alpha-2-macroglobulin,
External Links
MGI MGI:2449119

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001869

negative regulation of complement activation, lectin pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

P

From MGI

GO:0004866

endopeptidase inhibitor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002890
InterPro:IPR001599

F

From MGI

GO:0004867

serine-type endopeptidase inhibitor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0005515

protein binding

MGI:MGI:3762423
PMID:17920016[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q91ZX7

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009048

C

From MGI

GO:0005615

extracellular space

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011626

C

From MGI

GO:0007565

female pregnancy

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0635

P

From MGI

GO:0010951

negative regulation of endopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002890
InterPro:IPR001599

P

From MGI

GO:0010951

negative regulation of endopeptidase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

P

From MGI

GO:0019838

growth factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0019959

interleukin-8 binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0019966

interleukin-1 binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0030414

peptidase inhibitor activity

MGI:MGI:52427
PMID:1280217[2]

TAS: Traceable Author Statement

F

From MGI

GO:0043120

tumor necrosis factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01023

F

From MGI

GO:0048863

stem cell differentiation

MGI:MGI:4367296
PMID:19796622[3]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Liu Q et al. (2007) Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 56: 66-78 PubMed GONUTS page
  2. van Leuven F et al. (1992) The primary sequence and the subunit structure of mouse alpha-2-macroglobulin, deduced from protein sequencing of the isolated subunits and from molecular cloning of the cDNA. Eur J Biochem 210: 319-27 PubMed GONUTS page
  3. Nishiyama A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5: 420-33 PubMed GONUTS page
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