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MGI:4921505C17Rik

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Mus musculus (house mouse)

4921505C17Rik:RIKEN cDNA 4921505C17 gene
Synonyms:RICTOR
4921505C17Rik on MGI

GO terms

GO:0005085_!_guanyl-nucleotide_exchange_factor_activity (F) IEA with/from InterPro:IPR000651 [1]
GO:0005515_!_protein_binding (F) ISO with/from NCBI:NP_689969 [2]
GO:0005622_!_intracellular (C) IEA with/from InterPro:IPR000651 [1]
GO:0007275_!_multicellular_organismal_development (P) IEA with/from SP_KW:KW-0217 [3]
GO:0009790_!_embryonic_development (P) IMP [4]
GO:0030838_!_positive_regulation_of_actin_filament_polymerization (P) IMP [2]
GO:0031932_!_TORC2_complex (C) IPI [5]
GO:0032314_!_regulation_of_Rac_GTPase_activity (P) IMP [2]
GO:0050731_!_positive_regulation_of_peptidyl-tyrosine_phosphorylation (P) IMP [2]
GO:0051056_!_regulation_of_small_GTPase_mediated_signal_transduction (P) IEA with/from InterPro:IPR000651 [1]
GO:0051896_!_regulation_of_protein_kinase_B_signaling_cascade (P) IDA [4]

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Notes

References

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  1. 1.0 1.1 1.2 MGI annotation MGI:2152098
  2. 2.0 2.1 2.2 2.3 Jacinto E et al. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 6: 1122-8 PubMed GONUTS page
  3. MGI annotation MGI:1354194
  4. 4.0 4.1 Shiota C et al. (2006) Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell 11: 583-9 PubMed GONUTS page
  5. Jacinto E et al. (2006) SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127: 125-37 PubMed GONUTS page
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