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LISMO:TACY

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Contents

Species (Taxon ID) Listeria monocytogenes. (taxon:1639)
Gene Name(s) hly ( synonyms: hlyA, lisA )
Protein Name(s)
  • Listeriolysin O
  • LLO
  • Thiol-activated cytolysin
External Links
UniProt Identifier TACY_LISMO
UniProt Accessions P13128, Q48747, Q57096, Q57206,
EMBL X15127, M24199, X60035, U25446, U25449, U25452, AL591974,
PIR A43505, AC1100, S24231,
RefSeq NP_463733.1,
Pfam PF01289,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0044179

hemolysis of cells in other organism

PMID:3110067[1]

IDA: Inferred from Direct Assay

P

Fig 3. Lytic activity

complete

GO:0044179

hemolysis of cells in other organism

PMID:2509366[2]

IMP: Inferred from Mutant Phenotype

P

Table 1. Hemolysis reduced in mutant phenotype

complete

GO:0009405

pathogenesis

PMID:2509366[2]

IMP: Inferred from Mutant Phenotype

P

Fig. 4 Virulence reduced in mutant phenotype

complete

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

GO:0008289

lipid binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0446

F

GO:0009405

pathogenesis

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001869

P

GO:0009405

pathogenesis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0843

P

GO:0015485

cholesterol binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001869

F

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

GO:0019835

cytolysis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0204

P

GO:0020002

host cell plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1032

C

GO:0020002

host cell plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0375

C

GO:0033644

host cell membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1043

C

GO:0033644

host cell membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0380

C

GO:0044179

hemolysis in other organism

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0354

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Geoffroy C et al. (1987) Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes. Infect Immun 55: 1641-6 PubMed GONUTS page
  2. 2.0 2.1 Cossart P et al. (1989) Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation. Infect Immun 57: 3629-36 PubMed GONUTS page
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