![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
HUMAN:ZN423
Contents |
| Species (Taxon ID) | Homo sapiens (Human). (taxon:9606) | |
| Gene Name(s) | ZNF423 ( synonyms: KIAA0760, OAZ ) | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | ZN423_HUMAN | |
| UniProt Accessions | Q2M1K9, O94860, Q76N04, Q9NZ13, | |
| EMBL | BC112315, BC112317, AF221712, AB018303, | |
| RefSeq | NP_055884.2, | |
| IntAct | Q2M1K9, | |
| Ensembl | ENST00000262383, | |
| Pfam | PF00096, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
C |
Source: UniProtKB |
||||
| GO:0016563 |
transcription activator activity |
IDA: Inferred from Direct Assay |
F |
Source: UniProtKB |
||||
| GO:0016564 |
transcription repressor activity |
IDA: Inferred from Direct Assay |
F |
Source: UniProtKB |
||||
| GO:0016481 |
negative regulation of transcription |
IDA: Inferred from Direct Assay |
P |
Source: UniProtKB |
||||
| GO:0045941 |
positive regulation of transcription |
IDA: Inferred from Direct Assay |
P |
Source: UniProtKB |
||||
| GO:0003676 |
nucleic acid binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
F |
|||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
|||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
||||
| GO:0005634 |
nucleus |
IDA: Inferred from Direct Assay |
C |
|||||
| GO:0006351 |
transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0007219 |
Notch signaling pathway |
ISS: Inferred from Sequence or Structural Similarity |
P |
|||||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0007399 |
nervous system development |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0030154 |
cell differentiation |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0030513 |
positive regulation of BMP signaling pathway |
ISS: Inferred from Sequence or Structural Similarity |
P |
|||||
| GO:0042803 |
protein homodimerization activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000020028 |
F |
||||
| GO:0043565 |
sequence-specific DNA binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000020028 |
F |
||||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
IDA: Inferred from Direct Assay |
P |
|||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0046982 |
protein heterodimerization activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSRNOP00000020028 |
F |
| |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Huang S et al. (2009) ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome. Cancer Cell 15: 328-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Hata A et al. (2000) OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100: 229-40 PubMed GONUTS page