HUMAN:WNT6

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Species (Taxon ID)	Homo sapiens (Human). (taxon:9606)
Gene Name(s)	WNT6
Protein Name(s)	Protein Wnt-6
External Links
UniProt Identifier	WNT6_HUMAN
UniProt Accessions	Q9Y6F9, Q9H1J6, Q9H238,
EMBL	AY009401, AB059570, BT007456, BC004329, AF315943, AF079522,
PIR	JC7694,
RefSeq	NP_006513.1,
Ensembl	ENST00000233948,
Pfam	PF00110,

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0005578	proteinaceous extracellular matrix		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005201	extracellular matrix structural constituent		NAS: Non-traceable Author Statement		F	Source: UniProtKB
	GO:0004871	signal transducer activity		IEA: Inferred from Electronic Annotation		F	Source: InterPro
	GO:0007267	cell-cell signaling		NAS: Non-traceable Author Statement		P	Source: UniProtKB
	GO:0007275	multicellular organismal development		NAS: Non-traceable Author Statement		P	Source: UniProtKB
	GO:0007223	Wnt receptor signaling pathway, calcium mod...		IEA: Inferred from Electronic Annotation		P	Source: InterPro
	GO:0001658	branching involved in ureteric bud morphogenesis	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0001664	G-protein-coupled receptor binding	GO_REF:0000033		PANTHER:PTHR12027_AN0	F
	GO:0005102	receptor binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005817	F
	GO:0005102	receptor binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009143	F
	GO:0005576	extracellular region	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005817	C
	GO:0005576	extracellular region	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009143	C
	GO:0005576	extracellular region	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0964	C
	GO:0005576	extracellular region	GO_REF:0000029	NAS: Non-traceable Author Statement		C
	GO:0005578	proteinaceous extracellular matrix	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0272	C
	GO:0005578	proteinaceous extracellular matrix	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0111	C
	GO:0005615	extracellular space	GO_REF:0000033		PANTHER:PTHR12027_AN0	C
	GO:0005886	plasma membrane	GO_REF:0000033		PANTHER:PTHR12027_AN0	C
	GO:0007267	cell-cell signaling	GO_REF:0000029	NAS: Non-traceable Author Statement		P
	GO:0007275	multicellular organismal development	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005817	P
	GO:0007275	multicellular organismal development	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009143	P
	GO:0007275	multicellular organismal development	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0217	P
	GO:0009798	axis specification	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0009798	axis specification	GO_REF:0000033		PANTHER:PTHR12027_AN0	P
	GO:0009952	anterior/posterior pattern formation	GO_REF:0000033		PANTHER:PTHR12027_AN0	P
	GO:0010628	positive regulation of gene expression	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0010628	positive regulation of gene expression	PMID:20113781^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005817	P
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR009143	P
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0879	P
	GO:0016055	Wnt receptor signaling pathway	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0030182	neuron differentiation	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P56706	P
	GO:0031012	extracellular matrix	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	C
	GO:0042475	odontogenesis of dentine-containing tooth	PMID:20113781^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0048754	branching morphogenesis of a tube	GO_REF:0000033		PANTHER:PTHR12027_AN59	P
	GO:0060070	canonical Wnt receptor signaling pathway	GO_REF:0000033		PANTHER:PTHR12027_AN0	P
	GO:0060684	epithelial-mesenchymal cell signaling	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0061303	cornea development in camera-type eye	PMID:16258938^[2]	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:Q3C2H6	P
	GO:0070172	positive regulation of tooth mineralization	PMID:20113781^[1]	IMP: Inferred from Mutant Phenotype		P
	GO:0071300	cellular response to retinoic acid	GO_REF:0000024	ISS: Inferred from Sequence or Structural Similarity	UniProtKB:P56706	P
	GO:0072079	nephron tubule formation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0072080	nephron tubule development	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSMUSP00000006716	P
	GO:0072080	nephron tubule development	GO_REF:0000033		PANTHER:PTHR12027_AN59	P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Wang C et al. (2010) Effect of Wnt6 on human dental papilla cells in vitro. J Endod 36: 238-43 PubMed GONUTS page
↑ Fokina VM & Frolova EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev Dyn 235: 496-505 PubMed GONUTS page

[PMID:20113781-0] 1.0 ^1.1 ^1.2 Wang C et al. (2010) Effect of Wnt6 on human dental papilla cells in vitro. J Endod 36: 238-43 PubMed GONUTS page

[PMID:16258938-1] Fokina VM & Frolova EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev Dyn 235: 496-505 PubMed GONUTS page

[1]

[2]

HUMAN:WNT6

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